Co-Op, Myeloid Platform
About The Position
BlueRock Therapeutics LP is a clinical stage cell therapy harnessing the power of cell therapy to create a pipeline of new medicines for people suffering from neurological and ophthalmic diseases. Two of our novel investigational cell therapies, bemdaneprocel (BRT-DA01) for the treatment of Parkinsonâs disease and OpCT-001 for the treatment of primary photoreceptor diseases are clinical stage programs. BlueRock was founded in 2016 as a joint venture of Versant Ventures and Leaps by Bayer. Our culture is defined by the courage to persist regardless of the challenge, the urgency to transform medicine and deliver hope, integrity guided by mission, and community-mindedness with the understanding that we are all part of something bigger than ourselves. Our foundational science harnesses the ability to create and then direct the differentiation of universal pluripotent stem cells into authentic, functional cells that can be used as allogeneic cellular therapies to treat a broad array of diseases. We can also further engineer these cells, enabling them to produce enzymes, antibodies, and other proteins for additional therapeutic benefit. We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options. We are seeking individuals who are collaborative, thrive in a fun and dynamic culture, and are steadfast in the commitment to advance cutting-edge cellular therapies to impact patientsâ lives. The Myeloid Platform team is developing nextâgeneration microgliaâbased therapeutics for neurodegenerative and neuroinflammatory diseases. The Myeloid Platform Co-Op is responsible for the development of complex in vitro model of neurodegenerative diseases to further BlueRockâs drug development pipeline. This role places the coâop at the center of cuttingâedge research involving human iPSCâderived microglia, neural coâculture systems, and translational assay development. The successful candidate will act as part of the Myeloid platform team and will collaborate with other groups such as Discovery Analytics and Bioinformatics to generate sound scientific evidence to support and drive the companyâs preclinical pipeline.
Requirements
- Have (Currently enrolled in a degree program at an accredited college or university developmental biology, neuroscience, stem cell biology or related discipline).
- Possess the (Ability to work a 12 month assignment, full-time).
- Must be 18 years of age by the start of the internship/co-op.
- Must have transportation to the site in New York, NY, US.
- This position is intended to be on-site and candidates will be informed should anything change.
- Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities.
- Ability to work independently while contributing to collaborative project goals.
- Enthusiasm for learning new experimental techniques and contributing to platformâlevel innovation.
- Strong proficiency in aseptic technique, mammalian cell culture, and experience with primary cells or iPSCâderived cultures.
- Demonstrated ability to independently execute and troubleshoot experiments.
Nice To Haves
- Strongly preferred handsâon experience generating or working with neural organoids or other 3D culture systems.
- Background in microglia biology, macrophage biology, or myeloid differentiation.
Responsibilities
- Develop protocols for in vitro disease modelling of neurodegenerative disorders utilizing iPSC-based models
- Generation, expansion, and analysis of neural organoids and 3D microgliaâneuron spheroids.
- Perform differentiation, maintenance, and phenotypic characterization of iPSCâderived microglia, macrophages, and related myeloid lineages.
- Maintain cultures with strict aseptic technique and robust documentation.
- Support experimental pipelines that evaluate microglial responses in neurodegenerative contexts.
- Analyze data, prepare summaries, and present findings to the Myeloid Platform team.
- Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner, in accordance with the company quality management system.
- This position requires excellent communication skills
- This position requires on-site presence at least 5 days per week with occasional work on weekends and after hours.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
No Education Listed
