Clinical Research Operations Director

Headlands Research • Plymouth, MA

2d

About The Position

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.
Site Director – Transformational Clinical Research Leader
The Opportunity
Are you a seasoned clinical research leader ready to turn challenge into momentum? We are seeking a bold, hands-on Site Director to step into a clinical research site with untapped potential and lead its transformation into a high-performing, patient-centered operation.
This is not a maintenance role—it’s a build, elevate, and lead opportunity. You will have the autonomy, visibility, and support to implement best-in-class operational processes, mentor and inspire your team, and directly impact enrollment performance, data quality, and financial outcomes. If you thrive in environments where your leadership truly matters, this role offers the chance to leave a lasting mark.
What You’ll Do
As Site Director, you will serve as the operational and cultural heartbeat of the site—balancing strategy with execution and leadership with accountability.

Requirements

• Bachelor’s degree required
• 3+ years of experience in clinical trials (as a primary study coordinator, project coordinator, or similar role)
• Previous experience at the site-level required
• 3+ years of people management experience within the healthcare industry required
• Strong understanding of clinical trial operations and site-level financials

Nice To Haves

• Experience with change management techniques highly valued
• Highly detail-oriented with exceptional organizational skills
• Strong critical thinker who can prioritize, problem-solve, and execute under pressure
• Comfortable managing multiple priorities without losing sight of the big picture
• Tech-savvy with strong computer and reporting skills
• Clear, confident communicator with the ability to build trust across teams and external partners
• Customer- and patient-focused mindset

Responsibilities

• Coach, mentor, and develop site staff to reach their highest potential and operate as a cohesive, high-performing team
• Establish a culture of ownership, accountability, and continuous improvement
• Champion patient experience, retention strategies, and enrollment excellence
• Own site-level KPIs, including enrollment targets, financial performance, and quality metrics
• Implement and optimize operational systems and workflows to improve efficiency and outcomes
• Collaborate with the Business Development team and Sponsors/CROs to ensure the site has a consistent pipeline of awarded studies
• Oversee financial performance across trials
• Maintain accountability for invoicing accuracy and financial forecasting

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 101-250 employees