Clinical Pharmacology Intern (PhD)

AstraZeneca • Gaithersburg, MD

1d • $48 - $48 • Onsite

About The Position

We are looking for PhD students studying Clinical Pharmacology, Pharmacokinetics, Pharmaceutics, Pharmaceutical Sciences, PK/PD, DMPK or a related discipline for a 12-week internship role at our site in Gaithersburg, MD from May 18 2026 to August 7 2026. Position Description: Systematic Literature Review: Define search strategies, inclusion/exclusion criteria, and screen abstracts/full texts to identify studies on pharmacokinetics, pharmacodynamics, pharmacogenomics, and clinical response differences between Chinese and Caucasian populations. Data Extraction and Curation: Extract quantitative parameters (e.g., clearance, volume of distribution, bioavailability, half-life, exposure metrics like AUC/Cmax) and qualitative factors (e.g., allele frequencies for CYPs/UGTs/transporters, diet, BMI, co-medications), ensuring standardized units, metadata, and traceability. Critical appraisal and bias assessment: Evaluate study quality, population characteristics, analytical methods, and confounders; document heterogeneity and risk of bias to inform modeling assumptions. Manuscript preparation: Draft manuscript/conference abstract/poster.

Requirements

• PhD students studying Clinical Pharmacology, Pharmacokinetics, Pharmaceutics, Pharmaceutical Sciences, PK/PD, DMPK or a related discipline
• Candidates must have an expected graduation date after August 2026.
• Knowledge of pharmacokinetics, drug metabolism, drug transporter, and clinical pharmacology are required
• US Work Authorization is required at time of application.
• Ability to report onsite to Gaithersburg, MD site 3-5 days per week.
• This role will not provide relocation assistance.

Nice To Haves

• Experience with clinical trial design and clinical study are preferred
• Knowledge of PBPK is a plus.
• Enthusiasm for collaboration, cross-functional projects, public speaking, and presentation design.

Responsibilities

• Systematic Literature Review: Define search strategies, inclusion/exclusion criteria, and screen abstracts/full texts to identify studies on pharmacokinetics, pharmacodynamics, pharmacogenomics, and clinical response differences between Chinese and Caucasian populations.
• Data Extraction and Curation: Extract quantitative parameters (e.g., clearance, volume of distribution, bioavailability, half-life, exposure metrics like AUC/Cmax) and qualitative factors (e.g., allele frequencies for CYPs/UGTs/transporters, diet, BMI, co-medications), ensuring standardized units, metadata, and traceability.
• Critical appraisal and bias assessment: Evaluate study quality, population characteristics, analytical methods, and confounders; document heterogeneity and risk of bias to inform modeling assumptions.
• Manuscript preparation: Draft manuscript/conference abstract/poster.

Benefits

• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans

What This Job Offers

• Career Level: Intern
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees