Cancer Biology Omics Associate Data Scientist

MD Anderson • Houston, TX

27d • Hybrid

About The Position

Their primary responsibility will be to assist in the computational analysis of spatial single-cell transcriptomic and proteomic data from patient tumors generated from platforms such as CosMx Spatial Molecular Imager. Analyses will involve identifying spatially localized cellular niches, characterizing immune and epithelial cell states, modeling cell-cell communication, and uncovering pathways through which host-microbe interactions influence tumor biology.

Requirements

• Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field.
• Two years experience in scientific software or industry development/analysis.

Nice To Haves

• Knowledge of transcriptomics and proteomics is a plus

Responsibilities

• Analyzation and Integration Single-Cell and Spatial Omics Data
• Process and interpret single-cell RNA-seq and spatial proteomic and transcriptomic datasets to identify cellular states and tumor microenvironment features.
• Integrate multimodal data from platforms such as CosMx, MIBI, STOmics or GeoMx to uncover spatial niches and model cell-cell and host-microbe interactions.
• Apply analytical methods including clustering, differential expression, trajectory inference, and spatial proximity analyses.
• Computational Pipelines for Biological Insight Development
• Build, document, and maintain reproducible analysis pipelines in Python and R for high-dimensional omics datasets.
• Conduct pathway enrichment and network-based analyses to identify biologically relevant trends in cancer and immune responses.
• Generate publication-ready visualizations and figures that communicate key findings for manuscripts, grants, and presentations.
• Collaborate, Communicate, and Document Research Outputs
• Partner with interdisciplinary team members to interpret data, support experimental planning, and contribute to scientific publications.
• Present analytical results in lab meetings and project discussions to inform ongoing research directions.
• Maintain well-organized code, metadata, and supplementary materials to support reproducibility and data sharing.

Benefits

• The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Ambulatory Health Care Services
• Number of Employees: 5,001-10,000 employees