Biologist

Axle Informatics•Rockville, MD

15d•$80,000 - $85,000

About The Position

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH). Axle is looking to add a driven, flexible, organized, and meticulous Biologist to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Vaccine Production Program (VPP), Vaccine Research Center (VRC).

Requirements

B.S. in Biology, Chemistry, Chemical Engineering, Bioengineering, or related life science degree is required.
3-5 years of industry-level experience in cell culture development is required.
Experience with tech transfer of cell culture processes to manufacturing is required.

Responsibilities

Develop viral vaccines, recombinant proteins and/or virus-like particles or monoclonal antibodies.
Perform investigations and documentation of cell line growth, optimization of cell culture/fermentation conditions, cell culture technology development, improvement of cell culture platforms, modeling of cell culture behavior, troubleshooting of cell culture/fermentation processes, and tech transfer of defined cell culture/fermentation processes to the clinical production facility.
Capture process descriptions and results in lab notebooks, tech transfer documents, and technical reports.
Independently set-up and operate bioreactors and other cell culture equipment required for development studies.
Perform cell culture experimental studies.
Participate in project and laboratory meetings, keep current with compliance obligations, and be responsible for maintenance of the laboratory and equipment.
Contribute results and studies for publication in peer reviewed journals.
Develop experimental protocols (EP) for cell culture development studies for transients and/or stable cell line project and present finding, including:
Coordinate with Project leads and Project Management on EP goals
Design experimental conditions
Compile data into project-based presentations
Communicate results in project meetings
Serve as SME in new technologies initiatives, such as perfusion-based cell culture methods, and novel transient transfection techniques.
Contribute to Lab Operations initiatives including:
Responsible for FLEX2 bioanalyzer maintenance/troubleshooting
Responsible for upkeep of BIOS 16 Floor centrifuge maintenance and consumables supplies
Coordinate with Lab Operations manager on Lab Organizational efforts (e.g. 5S, KANBAN)