About The Position

Genetics has furnished the parts list for vertebrate development but not the instructions necessary to assemble those parts and create an embryo. The Laboratory of Theoretical Condensed Matter Physics, led by Dr. Eric D. Siggia, studies embryonic stem cells from mice and humans using methods derived from biophysics that permit the self-organization potential of stem cells to manifest itself. The assays reveal how signaling pathways integrate cues across space and time to pattern the developing embryo. Overview We seek a highly motivated Bioinformatics Assistant to join the Laboratory of Theoretical Condensed Matter Physics. The primary responsibility will be to process time-lapse datasets of mouse embryos acquired using light-sheet microscopy.

Requirements

  • Bachelor’s degree in Computational Biology, Computer Science, Bioinformatics, Biostatistics, Mathematics, or related field

Nice To Haves

  • Interest in biology/ biomedical research
  • Coding experience

Responsibilities

  • Use custom Python/MATLAB-based software developed in lab
  • Correct nuclear segmentations generated by state-of-the-art deep learning models
  • Classify cell types
  • Refine lineage tracking trees
  • Will learn/apply computational geometry techniques to extract 3D embryo structure
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