Biochemist II - BV Conjugation
About The Position
BioLegend is looking for a Biochemist to join the BV Conjugation team. The Biochemist II is responsible for performing antibody–fluorophore conjugations from small‑scale development batches to large‑scale production lots. This role requires strong technical proficiency in conjugation chemistry, consistent execution, excellent documentation practices, and active participation in continuous improvement initiatives. As manufacturing evolves toward increased automation and digital capabilities, the Biochemist II is also expected to be comfortable working with automated systems, electronic tools, and data‑driven workflows to support future‑ready operations. This position requires working in a red‑light environment to protect light‑sensitive dyes.
Requirements
- Bachelor’s degree in Biochemistry, Chemistry, or related field
- ≥ 2 years of independent, hands‑on experience performing high‑quality antibody–dye conjugation reactions
- Applicants must be currently authorized to work in the United States on a full-time basis for any employer.
Nice To Haves
- Comfortable working in a red‑light environment
- Strong understanding of conjugation chemistry and purification techniques
- Experience handling light‑sensitive fluorophores during reaction and purification while maintaining product integrity
- Experience with multiple conjugation chemistries
- Exposure to automation, SEC, and electronic batch records
- Experienced in manufacturing under ISO/GMP environment
Responsibilities
- Perform antibody–dye conjugations across scales; work accurately under red‑light when required; protect light‑sensitive fluorophores during reaction and purification
- Purify conjugates via SEC, desalting, and/or affinity chromatography
- Calculate concentrations, D/P ratios, yields, and other key quality metrics
- Drive yield and passing rate improvements
- Operate, maintain, and troubleshoot lab equipment
- Support semi‑automated instrumentation and electronic batch records
- Support adoption of automation and AI‑enabled tools that enhance accuracy and efficiency
- Review, verify, and update SOPs, batch records, and compliance documentation
- Participate in troubleshooting, root-cause investigations, and continuous improvement and lab safety initiatives
- Provide training to team members
- Other projects or responsibilities may be required
Benefits
- Medical, Dental, and Vision Insurance Options
- Life and Disability Insurance
- Paid Time-Off
- Parental Benefits
- Compassionate Care Leave
- 401k with Company Match
- Employee Stock Purchase Plan
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Number of Employees
5,001-10,000 employees
