Biochemist I/II - Conjugation

RevvitySan Diego, CA
2d$21 - $33Onsite

About The Position

BioLegend is looking for a Biochemist who will be responsible for performing antibody–fluorophore conjugations from small‑scale development batches to large‑scale production lots. This role requires strong technical proficiency in conjugation chemistry, consistent execution, excellent documentation practices, and active participation in continuous improvement initiatives. As manufacturing evolves toward increased automation and digital capabilities, the Biochemist II is also expected to be comfortable working with automated systems, electronic tools, and data‑driven workflows to support future‑ready operations. We are considering Biochemist candidates at Levels I and II.

Requirements

  • Associate's degree in Biochemistry, Chemistry, Biotechnology, or related scientific field with at least 2 years of experience in biotech manufacturing
  • Applicants must be currently authorized to work in the United States on a full-time basis for any employer.

Nice To Haves

  • Bachelor's degree in Biology, Chemistry, or a related scientific discipline with up to 1 year of experience in biotech product development or manufacturing
  • Strong understanding of conjugation chemistry and purification techniques
  • Experience handling light‑sensitive fluorophores during reaction and purification while maintaining product integrity
  • Experience with multiple conjugation chemistries
  • Exposure to automation, SEC, and electronic batch records
  • Experienced in manufacturing under ISO/GMP environment

Responsibilities

  • Perform antibody–dye conjugations across scales; protect light‑sensitive fluorophores during reaction and purification
  • Purify conjugates via SEC, desalting, and/or affinity chromatography
  • Calculate concentrations, D/P ratios, yields, and other key quality metrics
  • Drive yield and passing rate improvements
  • Operate, maintain, and troubleshoot lab equipment
  • Support semi‑automated instrumentation and electronic batch records
  • Support adoption of automation and AI‑enabled tools that enhance accuracy and efficiency
  • Review, verify, and update SOPs, batch records, and compliance documentation
  • Participate in troubleshooting, root-cause investigations, and continuous improvement and lab safety initiatives
  • Provide training to team members
  • Other projects or responsibilities may be required.

Benefits

  • Medical, Dental, and Vision Insurance Options
  • Life and Disability Insurance
  • Paid Time-Off
  • Parental Benefits
  • Compassionate Care Leave
  • 401k with Company Match
  • Employee Stock Purchase Plan
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