Bio-Analytics Scientist (CONTRACT BOS/CAMBRIDGE BASED ONLY)

Ring TherapeuticsCambridge, MA
2dOnsite

About The Position

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of self-assembly nanostructures by exploiting a family of naturally occurring commensal viruses to create the first re-doseable and targetable medicines utilizing a variety of payloads, such as oligos, small molecules, and DNA. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need. Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (NASDAQ:MCRB), , , and Indigo Agriculture. Position Summary: Ring Therapeutics is seeking a Bio-analytics Scientist to support bioanalytical and biophysical characterization of proteins. This fully laboratory based role will contribute to method execution, development, and data analysis using advanced chromatographic and light-scattering techniques to support research, development, and product characterization activities.

Requirements

  • Master’s degree with 5+ years of relevant industry experience preferably within ADCs.
  • Hands-on experience with cIEF and SEC-based methods , including MALS detection.
  • Ability to work independently and manage multiple analytical tasks.
  • Experience working in a regulated or quality-driven laboratory environment.

Nice To Haves

  • PhD with a minimum of 3 years of hands on practical experience in biologics development (pharmaceutical, biotechnology, or CRO).
  • Familiarity with AF4 / FFF-MALS systems and data interpretation.
  • Exposure to method validation, lifecycle management, and technology transfer.
  • Experience with ADCs, biological nanoparticles, or other protein therapeutics.

Responsibilities

  • Independently develop, execute and optimize bioanalytical and biophysical methods.
  • Lead routine analyses using cIEF, SEC-HPLC, SEC-MALS, FFF-MALS , LC-MS and other biophysical techniques.
  • Characterize critical quality attributes such as purity, aggregation, size, and charge variants.
  • Troubleshoot methods and instruments and propose technical improvements.
  • Draft and review protocols, technical reports, and SOPs.
  • Support investigations, comparability, and stability studies.
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