Associate Scientist/Scientist, Chemical Engineering

Agios Pharmaceuticals • Cambridge, MA

413d

About The Position

The Associate Scientist/Scientist in Chemical Engineering at Agios Pharmaceuticals will play a crucial role in the Chemistry Process Research and Development team. This position focuses on maintaining engineering services to support the development and manufacture of drug substances, including reaction optimization and crystallization process development. The role emphasizes collaboration with project leaders and chemists to enhance process understanding and accelerate development, ultimately contributing to therapies for rare diseases.

Requirements

• MS in chemical engineering or related field with 3 years' experience or PhD in chemical engineering or related field for Associate Scientist.
• OR MS in chemical engineering or related field with 6 years' experience or PhD in chemical engineering or related field with 2 years industry experience for Scientist.
• Strong attention to detail and the ability to multi-task in a fast-paced environment.
• Strong interpersonal skills and the ability to effectively work individually, within a cross-functional team.
• Strong oral and written communication skills.
• Strong team player that is solution-oriented with a positive, energetic, and proactive attitude.
• Record of scientific contribution through publications and presentations.

Nice To Haves

• Material science background in small molecule solid-state development, focusing on polymorph, co-crystal and salt screening, characterization and selection.
• Computational modeling and simulation experience to understand material physicochemical properties, reaction kinetics, and process scale down/up.
• Extensive experience in the application of various analytical instruments.
• Good knowledge for process safety evaluation.

Responsibilities

• Collaborate with a team to oversee and support drug substance manufacturing activities, including process design, optimization, scale-up, and technology transfer.
• Provide technical support within the Drug Substance group, including troubleshooting, investigations, process improvements, and the implementation of new manufacturing technologies.
• Assist in optimizing chemistry processes by utilizing Design of Experiments (DoE), production data, in-process controls (IPCs), and manufacturing information to enhance efficiency.
• Responsible for material characterization and analysis to support process understanding and development.
• Manage CROs/CDMOs for material solid-state development.
• Support crystallization development and establish PSD control strategies.
• Author and/or review pertinent SOP's and manufacturing process instructions.
• Manage external teams to address technical issues encountered in the above areas.

Benefits

• Deliberate Development for professional growth.
• Flexibility in work styles and schedules.
• Premium benefits package for health, wellbeing, and security.
• Competitive performance-based compensation including short- and long-term incentives.
• Psychological safety to share ideas and take data-informed risks.
• Commitment to diversity and fostering a welcoming workplace.
• Commitment to community involvement and support.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Education Level: Master's degree