Associate Scientist, Molecular and Cell Biology

Intellia Therapeutics, Inc. • Cambridge, MA

3d • Onsite

About The Position

Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together. We are looking for a motivated Associate Scientist to join our sgRNA screening team within the cross-functional Genomics and Computational Biology group. The sgRNA screening workflow is a critical step to nominate sgRNA candidates for most pipeline projects at Intellia. You will be part of a team responsible for testing sgRNAs in primary cells and immortalized cell lines, developing and executing cell and molecular biology assays to characterize genome editing outcomes. Additionally, you will collaborate with multiple groups such as Delivery Sciences and Gene Editing Platform to test novel delivery modalities and genome editing tools.

Requirements

• Excellent verbal and written communication skills.
• Excellent interpersonal skills.
• Excellent organizational skills and attention to detail.
• Excellent time management skills with a proven ability to meet deadlines.
• Strong analytical and problem-solving skills.
• Ability to function well in a high-paced environment
• BS or MSc degree in Biology or related disciplines
• BS or MSc degree in Biology or related disciplines with 4+ years (BS degree) or 2+ years (MS degree) of industry experience is required
• Extensive experience with cell culture and molecular biology assays is required

Nice To Haves

• Experience with primary hepatocytes and/or primary hematopoietic stem and progenitor cells is strongly preferred
• Hands-on experience with Illumina library construction, quantification, sequencing, and data QC is preferred
• Experience with liquid handling automation systems is preferred

Responsibilities

• Isolate, culture and/or bank primary cells and/or immortalized cell lines
• Transfect, transduce and/or electroporate cultured cells with genome editing reagents
• Develop, optimize and execute routine cell viability, mRNA and protein expression assays
• Quantify on- and off-target genome editing outcomes using various methods such as amplicon sequencing and ddPCR
• Work with team leads to ensure project timelines are met
• Record data in an electronic lab notebook and assist in intellectual property fillings
• Interpret findings and provide input to various projects
• Present updates in team meetings

Benefits

• performance-based annual cash bonus
• a new hire equity grant
• eligibility to be considered for annual equity awards the value of which are determined annually at the Company’s discretion

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 251-500 employees