Associate Scientist, Lentivirus Downstream Process Development

Johnson & Johnson Innovative MedicineSpring House, PA
Hybrid

About The Position

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. The Associate Scientist will support the development, characterization, and optimization of lentiviral vector downstream purification processes, contributing to process scale‑up, regulatory readiness, and technology transfer to manufacturing.

Requirements

  • Minimum of a Bachelor's degree in Biology, Biochemistry, Bioprocess Engineering, Virology, or a related scientific field is required
  • Minimum 1 year of experience doing protein and/or viral vector purification
  • Strong interpersonal skills, with the ability to closely collaborate with scientists and external teams

Nice To Haves

  • Master’s degree is preferred
  • Lentivirus/AAV downstream purification experience
  • Experience with ÄKTA FPLC purification systems
  • Experience with TFF systems

Responsibilities

  • Conduct small scale lentiviral vector production process development using material from mammalian cell culture.
  • Purification techniques will include depth filtration, affinity and/or Ion exchange (IEX) chromatography, and tangential flow filtration (TFF), sterile filtration etc.
  • Performing a range of viral vector process characterization studies to support process performance qualification (PPQ) and regulatory filing.
  • Assist the process technical transfer to manufacturing site as needed
  • Design, execute, analyze data and draft reports for studies
  • Stay current with relevant literature and evaluate new emerging technologies in viral vector production, incorporating them into processes as appropriate
  • Work in a team environment as well as individually to meet project timeline and objective.
  • Ensure data integrity through accurate and timely data capture/entry into appropriate electronic systems

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Number of Employees

5,001-10,000 employees

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