Associate Scientist, Lentivirus Downstream Process Development

Johnson & Johnson • Spring House, PA

428d

About The Position

The Associate Scientist, Lentivirus Downstream Process Development at Johnson & Johnson is responsible for developing and optimizing processes for lentiviral vector production. This role involves conducting small-scale production, purification, and characterization studies to support regulatory filings and process performance qualifications. The position requires collaboration with various teams and staying updated with emerging technologies in the field.

Requirements

• B.S. or master's degree in biology, Biochemistry, Bioprocess Engineering, Virology, or a related scientific field is required.
• Minimum 1 year of experience doing protein and/or viral vector purification is required.
• Strong interpersonal skills, with the ability to closely collaborate with scientists and external teams is required.

Nice To Haves

• Lentivirus experience is preferred.
• Hands-on experience with ÄKTA FPLC purification systems is highly preferred.
• Hands-on experience with TFF systems is highly preferred.
• Experience working with remote teams is preferred.

Responsibilities

• Conduct small scale lentiviral vector production process development using material from mammalian cell culture.
• Perform purification techniques including depth filtration, affinity and/or Ion exchange (IEX) chromatography, and tangential flow filtration (TFF).
• Conduct viral vector process characterization studies to support process performance qualification (PPQ) and regulatory filing.
• Assist in the technical transfer of processes to manufacturing sites as needed.
• Design, execute, analyze data, and draft reports for studies.
• Stay current with relevant literature and evaluate new emerging technologies in viral vector production.
• Ensure data integrity through accurate and timely data capture/entry into appropriate electronic systems.

Benefits

• Health insurance
• 401k
• Paid holidays
• Professional development opportunities

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree