Associate Scientist, iPSC Gene Editing

Eurofins USA PSS Insourcing Solutions • Boston, MA

4d • $37 - $41

About The Position

We are seeking a highly skilled and motivated Associate Scientist to join our diabetes team. This role focuses on iPSC gene editing and stem cell engineering to advance next-generation islet cell therapies. The ideal candidate has hands-on experience in human iPSC culture, gene editing, molecular biology techniques, and assay development.

Requirements

• B.S. in Stem Cell Biology, Cell Biology, Bioengineering, or related field with 3–4 years of relevant industry experience, or M.S. with 1–2 years of experience.
• Hands-on experience with human iPSC culture, gene editing, and molecular biology techniques.
• Proficiency in CRISPR gene editing, construct design, PCR-based assays, and flow cytometry.
• Experience with assay development (luciferase, ELISA, flow cytometry) and gene editing delivery methods.
• Strong organizational skills, accurate record-keeping, and excellent communication.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Nice To Haves

• Experience in pancreatic islet directed differentiation.
• Familiarity with transitioning research-grade processes to GMP-grade.
• Experience with electronic lab notebooks (ELN).

Responsibilities

• Perform routine iPSC culture, passaging, and media preparation.
• Develop and optimize CRISPR-based gene-editing workflows, including gRNA design and delivery.
• Generate and characterize clonal gene-edited iPSC lines using flow cytometry, PCR, ddPCR, dPCR, and NGS.
• Execute directed differentiation of iPSCs into pancreatic islets and assess drug substance parameters (cell counts, viability, metabolite measurements).
• Support assay development for on-/off-target analysis and drug substance evaluation.
• Collaborate cross-functionally to transfer R&D assays to GMP environments.
• Maintain detailed records, prepare reports, and contribute to SOP development.
• Execute workplans efficiently, meeting deadlines and supporting team goals.

Benefits

• Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Yearly goal-based bonus & eligibility for merit-based increases

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 5,001-10,000 employees