Associate Scientist In Vivo Immunology

GSK•Cambridge, MA

About The Position

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK’s long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life. The Associate Scientist in the in vivo immunology team will support the project team in spearheading GSK’s innovation of novel viral vaccines and platform programs. You will have the opportunity to work on the in vivo efforts on multiple viral vaccine programs and platforms within GSK and with external partners in a collaborative and matrix team. You will assist in writing in vivo study protocols, coordinate and initiate preclinical studies, conduct and analyze experimental results pertaining to the understanding of cellular mediated immune response and humoral immune response from novel vaccine candidates, formulations, and platforms.

Requirements

Bachelor’s degree in Immunology, Virology, Microbiology, Pharmaceutical Sciences, or related scientific field with 2+ years of lab experience.
1+ years of experience in conducting in vivo animal studies.
Experience working with aseptic techniques
Experience with laboratory notebook keeping

Nice To Haves

MS degree
Knowledge of vaccines, infectious diseases, or immunology
1+ years of experience in small rodent handling and drug administration, in-study blood sampling, necropsy, tissue harvest, and processing.
1+ years of experience in designing, executing, and analyzing cell-mediated immune response readouts using conventional or spectral flow cytometry.
A collaborative team player with strong interpersonal skills to work with diverse groups within the organization.
Experience with multiple immune-response related readout methods such as ELISA, ELISPOT, Luminex, and qPCR methodologies.
Proficient in using Microsoft Suite
Strong proficiency in English with clear, professional written and verbal communication; able to produce polished reports, emails and presentations.
Extremely organized with experience in documentation of study protocols and reports.

Responsibilities

Conduct dosing and tissue harvest from animal studies
Understand and execute in vivo study protocols, ensuring adherence to GSK and regulatory requirements for compliance with IACUC guidelines
Perform experiments characterizing cell-mediated immune response for preclinical immunogenicity or challenge studies using flow cytometry, ELISPOT assays and others.
Analyze experimental data and document them in detail using an electronic notebook
Write detailed protocols, procedures and work instructions to support immunology assays.
Contribute to the writing of technical sections of internal and external reports and contribute to scientific papers and patents
Help develop new experimental techniques based on project needs
Report results in team meetings, cross-function and cross-department meetings
Help with Lab management tasks including the ordering of materials, participation in operational meetings, routine equipment maintenance