Associate Scientist, Gene Therapy - in vivo Pharmacology
About The Position
The Gene Therapy Accelerator Unit at Biogen is searching for a committed, enthusiastic and dependable scientist to contribute to the generation of gene therapy clinical candidates for neurodegenerative and neuroinflammatory diseases. The incumbent will be part of a cross-functional team focused on transgene design and construction, optimization of capsid engineering and packaging to maximize transduction efficiency and tissue targeting, and scale-up of research grade material for in vivo efficacy and screening toxicology studies. He/She should have extensive experience in rodent handling/dosing, tissue collection and downstream analysis and should be able to plan and execute in vivo and in vitro experiments with high level of independency, organization and scientific rigor. He/she should be able to maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members. Direct responsibilities will include, but not be limited to: The Gene Therapy Accelerator Unit at Biogen is searching for a committed, enthusiastic and dependable scientist to contribute to the generation of gene therapy clinical candidates for neurodegenerative and neuroinflammatory diseases.
Requirements
- 5+ years of experience in the biotech/pharmaceutical industry with demonstrated in vivo skills
- Solid experience with peripheral (IV) and CNS delivery (IT, stereotaxis)
- Strong background in downstream analysis including IHC/IF, qPCR, WB, ELISA
Responsibilities
- In vivo validation of novel gene therapy clinical candidates
- Support the development of new AAV-related platforms
- Manage external CROs for outsourced preclinical studies
- Maintain organized and detailed electronic records
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
No Education Listed
Number of Employees
1,001-5,000 employees
