Associate Scientist, Analytical Development

Obsidian Therapeutics • Bedford, MA

48d

About The Position

We're looking for a highly motivated Associate Scientist with a strong background in cell therapy development to help drive the development of multiple cell therapy products in our pipeline targeting cancer. As part of our Technical Operations department you will be a vital part of a highly collaborative team working to achieve the Obsidian's vision by translating innovative science into medical breakthroughs for patients, starting with our lead program cytoTIL15 engineered to make TILs more effective for more patients. This is a unique opportunity in a well-funded pre-clinical company with blue-chip investors, field-leading advisors, best-in-class partners and an experienced team. You'll help us build a dynamic, innovative, passionate, collaborative, and successful organization focused on delivering transformative therapies in areas of greatest clinical need.

Requirements

• MS with 3+ or BS with 5+ years of relevant industry experience (degree in a relevant field biochemistry, cell biology, engineering, immunology).
• Experience in product release and characterization methods for cell and gene therapy products with a focus on long term cell-based assays, excellent aseptic technique, molecular and immunoassay (PCR / qPCR, ddPCR, ELISA, MSD), flow cytometry.
• Excellent organizational skills with an ability to manage multiple responsibilities in parallel, and communicate and prioritize effectively to deliver results within established timelines.
• Exceptional record-keeping skills.
• A highly collaborative working style.
• Tenacity, resilience, and drive to achieve company goals.
• Self-motivation and a proven ability to work with general direction to meet objectives and timelines, seeking clarity and support where needed.
• Flexibility; a willingness and ability to adapt to changes in priorities in a fast-paced, rapidly developing environment in order to advance our mission.
• Scientific curiosity and pursuit of continuous learning.

Nice To Haves

• Experience with multi-parameter flow cytometry assays.
• Demonstrated track record with analytical development supporting late-stage development of biologics and/or cell.
• Experience with analytical assay technical transfer and/ or qualification.

Responsibilities

• Train on and skillfully execute analytical methods to support characterization studies of iFeeder starting materials and cell therapy products for late phase clinical trials
• Help design and execute experiments in collaboration with process development team to support critical material characterization.
• Author and review technical documents and data presentation including, but not limited to, study protocols and reports and test methods.
• Interact with CDMO partners and serve as analytical PIP (person in plant) providing technical expertise and on-site support as needed
• Maintain excellent records of experiments, including timely Electronic Notebook entries.
• Collaborate well across the Obsidian organization and with external partners.
• Present experimental designs, data packages, and proposed timelines to project teams, management, and scientific teams.
• Perform work with limited direction following established procedures and an understanding of the underlying science.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Professional, Scientific, and Technical Services
• Number of Employees: 101-250 employees