Associate Scientific Director, Pharmacometrics
About The Position
Pharmacometrics analyses and insight are critical in the development of drug candidates, determination of product viability, and maximization of commercial value at Biogen. As the Associate Director, Pharmacometrics, you will provide pharmacometrics expertise for high-priority clinical development programs and support quantitative decision-making through advanced modeling and simulation. In this role, you will contribute to the pharmacometrics strategy across disease areas and serve as a key scientific resource to program teams and functional partners. You will report to the Head of Clinical Pharmacology, West Coast Hub (WCH) and collaborate closely with cross functional teams to ensure pharmacometrics analyses are appropriately applied to program needs.
Requirements
- PhD in Pharmacology, Pharmacokinetics, Pharmaceutics or a related quantitative discipline.
- 5+ years of relevant industry experience applying population PK/PD and other advanced quantitative methodologies to decision making.
- Deep and extensive experience with advanced population PK/PD methodology
- Strong understanding of the clinical pharmacology principles and methodologies and their application in drug development
- Solid knowledge of the drug development process and regulatory expectations for pharmacometrics analyses
- Ability to interpret quantitative results and translate analyses into actionable program insights
- Hands-on experience with pharmacometrics software tools such as NONMEM, Monolix, and R.
Nice To Haves
- Experience with mechanistic or systems pharmacology models is a plus.
Responsibilities
- Provide pharmacometrics expertise to activities throughout the drug development lifecycle and effectively collaborate with cross functional teams
- Execute advanced pharmacometrics analyses, with emphasis on PK/PD modeling and simulation and exposure-response analysis for high priority programs
- Identify opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy and safety
- Contribute to Model Informed Drug Development (MIDD) activities to support dose selection, regimen optimization and clinical trial design
- Communicate the pharmacometrics analysis results to program teams to support data-driven decision-making process
- Mentor and guide Clinical Pharmacology and Pharmacometrics colleagues on pharmacometrics analyses methodologies
- Serve as a lead author and key contributor for pharmacometrics sections of clinical and regulatory documents
- Publish in scientific journals and present at internal and external scientific events
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
