Associate Research Scientist II

Exact Sciences • Palladio, PR

8d • $87,000 - $130,000

About The Position

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others. Position Overview The Associate Research Scientist II, with limited guidance from more experienced scientists, works individually or in collaboration with others on multiple projects which are moderate to complex in scope. The Associate Research Scientist II plays an active role in planning of projects and experiments and is often the technical lead responsible for the successful execution of project(s). This role is responsible for conducting hands on experimentation and the analysis and presentation of data. Working in a team setting, the Associate Research Scientist II, will primarily be involved in Research and Development projects actively participating in translating research ideas and concepts into the product development pipeline towards development of diagnostic assay products. This position will be primarily responsible for creating clinical research datasets using our proprietary DNA sequencing methodologies for cancer detection, in order to support related products. The position may also contribute to development and optimization and/or characterization of all aspects of clinical sample testing, e.g. specimen processing, nucleic acid isolation, library construction, target enrichment, and target detection workflows. Key responsibilities include operating NGS workflows and associated automation methods, troubleshooting technical issues, managing experiments, ensuring data quality, maintaining thorough documentation such as protocols and technical reports, and collaborating effectively with cross-functional teams.

Requirements

• Master’s degree in Medical Technology, Clinical Laboratory Science, Chemical/Physical/Biological Science or related field; or Bachelor’s degree in Life Sciences, Medical Technology, Clinical Laboratory Science, Chemical/Physical/Biological Science, or related field and 2 years of experience in lieu of a Master's degree.
• 3+ years of relevant experience.
• 3+ years of hands-on experience in molecular biology and/or biochemical techniques.
• Basic understanding of GMP, ISO, and Quality Systems.
• Demonstrated ability to apply statistical and mathematical methods in biology/genetics/genomics; including statistical software, such as JMP.
• Applicants must be currently authorized to work in country where work will be performed on a full time or part-time basis. We are unable to sponsor or take over sponsorship of employment visas at this time. (U.S. Only)
• Demonstrated ability to perform the Essential Duties of the position with or without accommodation.

Nice To Haves

• 2 or more years of experience in medical device/IVD, biotech, life science or pharmaceutical industry.
• Hands-on experience with DNA extraction, quantification, and physical analysis (e.g. electrophoresis or spectrophotometry).
• Experience using PCR, qPCR, or ddPCR for sample analysis.
• Demonstrated ability to plan, execute, analyze, and interpret experiments.
• Hands on experience with DNA library construction and target enrichment for analysis on Next Generation Sequencing platforms a plus.
• Familiarity with assay development, optimization, and validation processes.
• Proven ability to work cross-functionally with R&D, bioinformatics, clinical operations, and quality teams.

Responsibilities

• Conduct bench level experiments within a specific product or technology area and identifies problems and discrepancies.
• With some guidance, plan and analyze results of bench level experiments within a specific product or technology area.
• Operate scientific instrumentation related to performance of duties and notify appropriate personnel of any problems.
• Effectively utilize and apply methods or technologies and provide ideas for new techniques, when appropriate.
• Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures.
• Provide technical input and participates in decisions affecting project planning and experimental design.
• Prepare and provide information and generate data for scientific abstracts/conferences/project meetings/publications.
• Follow research plans and experimental outlines to write experimental protocols and perform laboratory experiments.
• Maintain lab notebook in a complete and consistent manner, following all legal, ISO, and QSR requirements, as well as keeping clear and complete.
• Prepare reports and documentation providing the analysis or summarization of experimental results and outcomes to supervisor, technical teams/groups, or project teams.
• Present experimental results, scientific ideas and findings, information, and updates at project or departmental meetings.
• Present clear project summaries and outcomes in written and verbal formats to supervisor and other members of the scientific team.
• Work on problems of diverse scope in which analysis of data requires evaluation of identifiable factors.
• Work on individual assignments and with project team members, as appropriate, to meet department and project objectives.
• Work within project timeframes that are established collaboratively by team members.
• Exercise discretion and independent judgement to interpret results, analyze data, and present findings in a professional and knowledgeable manner.
• Ability to train and mentor junior level research associates.
• Ability to organize, present, and convey moderate problems or issues.
• Ability to communicate clearly with supervisor and group members.
• Excellent presentation skills.
• Ability to collaborate and work effectively within team and department.
• Strong attention to detail skills.
• Ability to effectively work on several varied projects at one time, with frequent changing priorities.
• Successful in analytical, problem solving, and decision-making skills.
• Successful in technical proficiency, scientific creativity, collaboration with others, and independent thought.
• Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
• Support and comply with the company’s Quality Management System policies and procedures.
• Regular and reliable attendance.
• Ability to work nights and/or weekends, as needed.
• Ability to lift to 20 pounds for approximately 5% of a typical working day.
• Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 50% of a typical working day.
• Ability to grasp with both hands; pinch with thumb and forefinger; turn with hand/arm; reach above shoulder height.
• Ability to comply with any applicable personal protective equipment requirements.
• Ability to use various types of laboratory equipment including microscopes, microtomes, blades, strainers, pipettes for extended periods of time.
• May perform repetitious actions using lab tools.
• Ability to use near vision to view samples at close range.
• May be exposed to hazardous materials, tissue specimens and instruments with moving parts, lasers, heating and freezing elements, and high-speed centrifugation.
• Ability and means to travel between Exact Sciences locations.
• Ability to travel 5% of working time away from work location, may include overnight/weekend travel.

Benefits

• paid time off (including days for vacation, holidays, volunteering, and personal time)
• paid leave for parents and caregivers
• a retirement savings plan
• wellness support
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees