Associate Research Scientist | Functional Genomics
About The Position
JAX/NYSCF is seeking an Associate Research Scientist to join the Functional Genomics team as part of the NYSCF Global Stem Cell Array™, a robotic system that automates both iPSC derivation, gene editing, and downstream differentiations. The Associate Research Scientist will contribute to an innovative project centered on phenotyping cardiomyocytes derived from genetically diverse human induced pluripotent stem cell (hiPSC) lines. This work aims to uncover the genetic basis of cardiotoxic responses and to advance predictive models of cardiovascular health through high-throughput functional screening, transcriptomics, and metabolomics. The project is highly collaborative, involving multidisciplinary teams across several institutions. The primary focus of the work you’ll do at JAX/NYSCF is developing automated protocols for the derivation/culture of iPSC-derived cardiomyocytes, drug testing, and sample preparation for downstream analyses, including imaging and single-cell sequencing. We want candidates with extensive expertise in human pluripotent stem cell culture, directed differentiation into cardiomyocytes, and functional assays. Experience with cell culture automation (including liquid handling systems) or high-throughput assays is a major plus. This role offers a unique opportunity to work with state-of-the-art screening technologies and automated platforms while contributing to impactful translational research in cardiac safety pharmacology and personalized medicine.
Requirements
- PhD +3 years of work experience in Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline.
- Experience with induced pluripotent stem cells or cardiomyocytes/ iPSC-derived cardiomyocytes.
- Strong communication skills, with the ability to clearly explain research findings and methodologies in both written and verbal formats, as well as effectively discuss, troubleshoot, and resolve experimental challenges with team members and collaborators.
- Ability to follow and adapt protocols accurately.
- Excellent documentation and data management practices.
Nice To Haves
- Experience in differentiation of iPSC culture in cardiovascular lineages.
- Exposure to automated cell culture systems (liquid handlers)
- Electrophysiology experience is a plus
- Flow cytometry
Responsibilities
- Design, optimize, and execute experiments to advance a high-throughput iPSC-derived cardiomyocyte platform
- Culture and expand iPSCs, generate iPSC-derived cardiomyocytes, and assess cardiomyocyte quality using automated liquid handling systems
- Apply strong scientific knowledge and analytical skills to monitor, troubleshoot, and refine experimental workflows in real time.
- Independently conduct literature reviews to identify and propose innovative experimental methods, procedures, or technologies
- Contribute to project planning by preparing budgets, timelines, and resource estimates for supplies and equipment
- Lead multiple, concurrent project components, ensuring progress toward research goals
- Evaluate and document results, adapt methodologies as needed, and maintain compliance with regulatory standards
- Communicate research goals and findings effectively, guiding team members and informing collaborators on past and future directions
- Coordinate with external partners to explore new research opportunities
- Foster a collaborative environment by sharing expertise and demonstrating openness to learning from others
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
Number of Employees
1,001-5,000 employees
