Associate Principle Scientist

IQVIA • Durham, NC

3d

About The Position

We are seeking Senior Scientist, Antibody Characterization (SPR/BLI) to join IQVIA Laboratories at Durham, NC . We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development. Job Summary: The Senior Scientist will lead high‑throughput biophysical characterization of antibodies generated from discovery and affinity maturation campaigns, supporting the selection of high‑quality therapeutic leads through advanced biomolecular interaction analyses.

Requirements

• PhD with relevant experience or MS with 3+ years of experience in Biology, Biochemistry, Molecular Biology, Chemical Engineering, Immunology, or a related life science field, preferably within biotech or pharmaceutical environments.
• Extensive hands‑on experience with protein–protein interaction analysis using label‑free biosensor technologies
• Mastery of SPR platforms with demonstrated experience using Carterra LSA and Biacore 8K systems
• Strong understanding of antibody biophysical characterization and developability considerations
• Ability to operate, maintain, and troubleshoot complex SPR instrumentation independently
• Excellent analytical, communication, and leadership skills with the ability to manage multiple priorities

Nice To Haves

• Experience with BLI instrumentation and automated laboratory systems is a plus
• Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

Responsibilities

• Perform full biophysical characterization of antibodies from discovery and affinity maturation campaigns in a high‑throughput environment
• Supervise, train, and mentor team members in the design and execution of biomolecular interaction analyses
• Independently design, execute, and troubleshoot SPR‑ and BLI‑based assays including kinetics, affinity, blocking, competition, and epitope binning
• Analyze, interpret, and present complex data sets to support antibody lead selection across multiple concurrent programs
• Develop, optimize, and standardize novel assays to support custom antibody discovery workflows
• Collaborate with Discovery and Bioinformatics teams to guide R&D efforts related to antibody developability

Benefits

• We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs.
• We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey.
• To learn more about our benefits, visit https://jobs.iqvia.com/benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees