Associate Medical Director of US Evidence Generation

Alnylam Pharmaceuticals

About The Position

We are seeking a strategic and scientifically driven Associate Medical Director of US Evidence Generation to focus on the development and execution of US real world evidence (RWE) strategies that support the value proposition of Alnylam’s products across the ATTR franchise. This US-centric role will collaborate cross-functionally to generate impactful evidence that informs clinical practice and demonstrates continued value to US HCPs/KOLs, payers and health systems. As a US evidence generation leader, the candidate will partner with the Value Evidence Strategy team (VESt) to provide medical leadership for strategic projects under their direct responsibility. They will also support the planning and execution of RWE projects conducted by external vendors.

Requirements

Advanced degree (PharmD, PhD, MD) with strong preference for candidates with experience in cardiology and/or RWE generation
Minimum of 5 years of experience in medical affairs within the pharmaceutical or biotech industry, including experience in field medical roles, strategy development and evidence generation
Excellent interpersonal, communication, and collaboration skills, with the ability to engage effectively with internal and external stakeholders
Strong scientific acumen, ability to function autonomously, and succinctly communicate with cross-functional stakeholders
Experience managing budgets and external partnerships related to RWE projects
Experience supporting both product launches and lifecycle management with RWE
Entrepreneurial spirit and resourcefulness
Excellent project management skills
Ability to travel as needed to fulfill job responsibilities

Responsibilities

RWE Strategy Development:
Participate in strategic planning by supporting the development and refinement of the US RWE strategic plan, ensuring alignment with broader Medical Affairs and cross-functional objectives
Identify and prioritize strategic US evidence gaps in close collaboration with cross functional team that includes Medical, Market Access, US Commercial Sales and Marketing
Partner with the US Medical field teams to assess and map RWE generation opportunities and capabilities across KOLs, payers and health systems
Maintain a US KOL database of HCPs and health systems with interest and insights into ATTR evidence generation
Support data-driven refinement of the US RWE strategic plan, content and messages through analysis of key performance indicators (KPIs) related to knowledge, attitudes and practices of US stakeholders through advisory boards, field insight generation and feedback from professional medical associations
Study Design & Execution:
In coordination with the VESt, lead, design, and deliver RWE analyses while serving as a clinical subject matter expert to ensure scientific integrity of conducted RWE research
Cross-Functional Collaboration:
Ensure coordination among matrixed teams including Medical Affairs, Commercial, Publications, Materials Review Boards, Compliance, and external partners to incorporate RWE findings into publications and field materials
Participate in the development of abstracts, manuscripts, and presentations for scientific congresses and peer-reviewed journals
External Engagement:
Lead vendor selection and collaborate with external experts, academic institutions, and data vendors to execute high-quality RWE studies
Data Governance & Compliance:
Ensure all RWE activities comply with relevant Alnylam SOPs, US regulatory, legal, and ethical standards, including data privacy and local guidelines

Benefits

We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match.
Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.
We also offer generous family resources and leave.

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