Associate Engineer - Pilot Plant

Amgen Inc. • Cambridge, MA

38d

About The Position

Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Associate Engineer - Pilot Plant What you will do Let's do this! Let's change the world! The role provides hands-on operational and technical support within the pilot plant. The position bridges engineering and scientific disciplines to ensure robust process performance, equipment reliability, and successful technology transfer from process development to manufacturing scale. The individual will contribute to process optimization, experimental execution, and equipment design to enable efficient and reproducible biologics production.

Requirements

• High school diploma / GED and 6 years of engineering or bioprocess operations experience OR
• Associate's degree and 4 years of engineering or bioprocess operations experience OR
• Bachelor's degree

Nice To Haves

• Hands-on experience with pilot plant or manufacturing-scale bioprocess equipment (bioreactors, filtration skids, chromatography systems, etc.)
• Familiarity with cell culture or fermentation processes, including setup, inoculation, monitoring, and harvest operations.
• Experience with scale-down models for process development and technology transfer.
• Understanding of GMP and biopharmaceutical production environments.
• Demonstrated ability to troubleshoot and optimize process equipment and control systems.
• Knowledge of change control, nonconformance management, and validation principles.
• Strong analytical and problem-solving skills using data-driven methods.
• Flexibility to support pilot plant operations outside of standard working hours as needed (evenings, weekends, and on-call support).

Responsibilities

• Perform day-to-day pilot plant equipment involving upstream and downstream bioprocess equipment.
• Support and troubleshoot process deviations, ensuring minimal disruption to pilot campaigns.
• Partner with process scientists to plan and execute engineering runs and process characterization studies.
• Provide hands-on support for equipment setup, operation, calibration, and maintenance.
• Implement preventive maintenance and reliability improvement initiatives across pilot-scale bioreactor systems and support equipment.
• Identify equipment risks and drive the development of risk mitigation strategies to enhance process consistency.
• Analyze experimental and process data from both pilot and bench-scale studies to identify performance trends and opportunities for optimization.
• Apply engineering and bioprocess principles to improve process performance, including yield, scalability, and robustness.
• Utilize data-driven problem-solving methods (e.g., statistical analysis, design of experiments) to inform process and equipment improvements.
• Lead or participate in initiatives to improve process efficiency, reduce cycle times, and enhance product quality.
• Support new product introductions and technology transfers by assessing process fit and implementing pilot-scale modifications as needed.
• Collaborate cross-functionally with process development, manufacturing, and engineering teams to ensure smooth scale-up and knowledge transfer.
• Maintain accurate and complete documentation of experimental work, pilot operations, and equipment modifications in compliance with GMP and internal quality systems.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Number of Employees: 5,001-10,000 employees