Associate Director Therapeutic Area Genetics

Regeneron Pharmaceuticals • Tarrytown, NY

37d • Onsite

About The Position

We are seeking a Scientist to join our Neuroscience and Ophthalmology Therapeutic Area Genetics (TAG) team. The position will take on responsibilities for the design, execution, and interpretation of genetics studies focusing on neurological, ophthalmological, and auditory diseases. You will work closely with other teams in the Regeneron Genetics Center and Regeneron at large and be primarily responsible for designing, contributing to the execution of, and interpreting large and complex human genetic studies in the therapeutic areas. We hope you are excited by the opportunity to play a role in the development and implementation of innovative translational sciences and identify new therapeutic targets through genetic approaches. As a Scientist, a typical day might include the following: Applying human genetics to target discovery, selecting indications for drug programs, and identifying subgroups of patients who are more likely to respond to treatment through genetic analyses. Working with a multidisciplinary genetics team consisting of human genetics scientists, physician scientists, bioinformaticians, statistical geneticists, and other team members to design, execute, and interpret genetics studies in ophthalmology. Working in close collaboration with other Therapeutic Area Genetics team members and forming a strong partnership with Genome Informatics, Analytical Genomics, Clinical Informatics, and other RGC teams to deliver on complex, top-quality scientific endeavors in these Therapeutic Areas. Generating, summarizing, and presenting results in internal and external meetings to a variety of audiences. Leading or contributing to the writing of scientific reports and publications. Representing the TAG team in cross-functional initiatives within RGC and Regeneron. Collaborating with external industry and academic partners in scientific consortia.

Requirements

• You have demonstrated the ability to design and lead human genetics studies delivering medically relevant findings in a team-based environment.
• You use medical knowledge to define relevant phenotypes for genetic association studies and to formulate innovative and important research questions.
• You have experience leading complex human genetics research endeavors, have knowledge of different study designs and analyses including GWAS, exome, or genome sequencing in cohort, case-control, or family-based studies, and have the ability to integrate different data resources to translate initial findings.
• You have an interest in understanding the genetic basis and causes of Neurological, Psychiatric, Ophthalmological, and Aging-related diseases and translating this knowledge into therapeutic insights. An outstanding candidate will have previous experience with phenotypes related to these diseases.
• You thrive working in a highly interactive environment with a diverse team of colleagues.
• You have outstanding communication skills and an ability to summarize and present the results of human genetic studies to a variety of audiences.
• To be considered for this opportunity, you must have a PhD or MD/PhD with a strong background in and knowledge of human genetics or genetic epidemiology.
• An outstanding candidate will be a PhD with training and 7+ years of experience in translational human genetics, genetic epidemiology (or related disciplines), and strong quantitative skills.
• Familiarity with the applications of statistical genetics to gain medically actionable insights including polygenic risk scores, quantitative traits analyses, and Mendelian randomization, and familiarity with command-line interface, programming languages, and statistical software (eg. Python, R) is preferred.

Nice To Haves

• The outstanding candidate will have experience with the use of genetics in combination with other "omics" technologies (eg. epigenetics, proteomics, RNA-seq) and experience working on cloud computing interfaces with large-scale datasets such as UKB, FinnGen, or AllOfUs.

Responsibilities

• Applying human genetics to target discovery, selecting indications for drug programs, and identifying subgroups of patients who are more likely to respond to treatment through genetic analyses.
• Working with a multidisciplinary genetics team consisting of human genetics scientists, physician scientists, bioinformaticians, statistical geneticists, and other team members to design, execute, and interpret genetics studies in ophthalmology.
• Working in close collaboration with other Therapeutic Area Genetics team members and forming a strong partnership with Genome Informatics, Analytical Genomics, Clinical Informatics, and other RGC teams to deliver on complex, top-quality scientific endeavors in these Therapeutic Areas.
• Generating, summarizing, and presenting results in internal and external meetings to a variety of audiences.
• Leading or contributing to the writing of scientific reports and publications.
• Representing the TAG team in cross-functional initiatives within RGC and Regeneron.
• Collaborating with external industry and academic partners in scientific consortia.

Benefits

• comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels!

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees