Associate Director, Oncology Clinical Biomarker Asset Lead, Translational Development

Bristol Myers Squibb•Princeton, NJ

56d•Hybrid

About The Position

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Bristol Myers Squibb has pioneered the development of immuno-oncology therapies and continues to diversify in drug development for the treatment of cancers. Our world-class Translational Development organization is exploring new aspects of tumor and immune biology to create tailored, individualized treatment strategies that will offer the greatest possible benefit to patients. We are looking for experienced translational scientists to help drive improved understanding of disease biology, mechanism of action, and predictive biomarkers in our late-stage clinical oncology portfolio. Ideal candidates will possess a strong scientific background, effective communication skills, and experience working in a matrixed industrial environment. Seeking candidates with Biomarker Lead late stage clinical trials for Phases II/III preferred. Regulatory submissions drug approvals in solid tumor space also highly desirable. The Clinical Biomarker Asset Lead role will be responsible for development and execution of translational strategies in solid tumor oncology for assigned programs. Key responsibilities of this role are to act as a lead scientist to implement and deliver on biomarker strategies for clinical programs, develop reports and publications on translational data generated to support asset development and contribute to regulatory submissions. This individual will work on cross-functional project teams to drive execution of translational/biomarker plans working with disease and lab scientists, as well as BMS members from clinical, medical, commercial, regulatory, and diagnostics. Individual will also engage with external academic collaborators/Key Opinion Leaders (KOLs). This position can be located in Princeton/LVL, NJ, Summit NJ, or Cambridge, MA

Requirements

In-depth understanding of solid tumor oncology with knowledge of current and evolving clinical landscape and competitive scenarios
Strong scientific background with understanding of clinical, translational, and mechanistic data with proven track record of publications
Understanding of early or late-stage drug and translational development process; including experience with implementing a biomarker strategy
Clinical protocol authoring and review of regulatory documents.
Working knowledge of technological platforms covering biomarker measures including but not limited to genomics, gene expression, immune profiling, and flow cytometry.
Excellent data analysis and problem-solving skills
Exceptional verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, scientific presentations and regulatory submissions (INDs/NDAs) with ability to synthesize complex scientific concepts into simple communication points
Proven scientific/project leadership expertise and experience working in global teams and managing people/projects
Ph.D. in Oncology/immunology or related field with
5-8+ years of industry experience
3-5 years in oncology/biomarkers/translational or correlative research
Requires comprehensive knowledge of principles, concepts and / or methodologies within drug discovery or clinical development
Has significant understanding of the role of translational research/medicine and clinical biomarkers in drug development
Demonstrated knowledge of oncology and/or tumor-immunology disease biology

Nice To Haves

Seeking candidates with Biomarker Lead late stage clinical trials for Phases II/III preferred.
Regulatory submissions drug approvals in solid tumor space also highly desirable.

Responsibilities

Integrate translational research and clinical development, developing biomarker strategies in alignment with clinical development objectives, leading efforts for data generation and interpretation and for communication to the development teams.
Responsible for understanding external research environment, partnering with other functions both internally and externally to coordinate the execution of Translational development deliverables.
Engages functional groups to develop, champion, implement and align biomarker strategies for development projects in support of the overall R&D portfolio goals.
Effectively engages with teams and matrix leadership to define, revise and progress translational biomarker plans.
Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving towards delivering key data and interpretations essential for decision making.
Delivers high quality biomarker strategies for understanding mechanism of action/resistance, target engagement, pharmacodynamics endpoints and patient selection.
Ensures the output of the biomarker plans meets established project standards.
Engages team members to ensure alignment of biomarker strategies with clinical operational plans and with functional area capabilities to execute and deliver on robust translational biomarker data package to support trial and program
Builds productive relationships with team members that interact with the translational clinical biomarker group.
Effectively interfaces with functional areas to ensure strategic alignment and to identify resources needed to deliver on biomarker goals
Productively engages with external collaborators and scientific KOLs to support translational goals.
Communicates key biomarker program information, risks, and milestones, and manages information flow across team members

Benefits

We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Medical, pharmacy, dental and vision care.
Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
Financial well-being resources and a 401(K).
Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
Parental, caregiver, bereavement, and military leave.
Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
Other perks like tuition reimbursement and a recognition program.

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