Associate Director, Computational Genomics

Vertex Inc.•Boston, MA

2d•Hybrid

About The Position

To advance the development of transformative therapies for people with serious and life-threatening diseases, we are seeking an experienced computational biologist to lead the Boston-based computational genomics team, as part of the global Data and Computational Sciences organization. You and your team will focus on making biological discoveries by leveraging large-scale genomic and human genetic data to advance our drug discovery and development programs. As the leader of a team of 5, you will partner with leadership at the Boston Research site and disease project teams to drive project success in a fast-paced environment in areas such as target validation, pre-clinical model development, and characterization of novel therapeutics. You will also work closely with leaders across the global computational genomics teams and the Data and Computational Sciences department to develop technical best practices, define future directions for the team, and contribute to strategic initiatives. This is an on-site or hybrid eligible position requiring at least 3 days/week onsite.

Requirements

Advanced understanding in the fields of genomics, human genetics, statistics and/or computational biology, such as bulk and single cell transcriptomics, pooled variant screening, genome-wide association studies.
A proven track record in the analysis, visualization, and interpretation of large-scale genomic data in a drug development context.
Excellent scientific critical thinking, with the ability to understand the value, risks, and challenges of various approaches, synthesize and interpret complex data, and propose recommendations to drive forward progress.
Demonstrated ability to work across cross-functional teams, ensuring proactive collaboration and timely progress.
Superior communication skills demonstrating conﬁdence and versatility in presenting verbally to diverse audiences and writing technical documents, including experience presenting to senior and executive leadership.
A team-oriented growth mindset that welcomes feedback from others and supports other team members; a positive attitude that enthusiastically tackles and overcomes challenges.
Highly skilled in mentoring others, resolving technical problems, maintaining procedural and ethical standards, and cultivating healthy team morale.
PhD degree (or Master’s degree) in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field with 5+ years (or 8+ years for Master’s degree) of productive, relevant industry experience and 2 years of management experience, or the equivalent combination of education and experience.
Demonstrated leadership abilities, such as management of a high-performing team, leadership of a scientific project, mentorship of junior scientists.

Responsibilities

As the Computational Genomics team lead for Boston Research, you will work with your team members and disease project teams to identify and prioritize key project questions, design genomic studies, and interpret results to drive project progress.
As a part of the global leadership for the Computational Genomics team, work across sites to prioritize global needs to maximize impact across the global research portfolio.
Oversee computational genomic activities of your team, including providing scientific guidance, resource management, and leadership to ensure impactful and timely completion of studies, with adherence to data integrity and documentation policies.
Ensure continuous talent development to attract, retain, and develop your team members.
Partner across the rest of the Data & Computational Sciences department to prioritize, develop, and evolve computational methods and best practice guidelines for key analyses.
Establish and maintain productive relationships with key stakeholders such as the Boston Research leadership across the organization.

Benefits

This role is eligible for an annual bonus and annual equity awards.
Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

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