Associate Director

Frontage Laboratories • Exton, PA

10d • Onsite

About The Position

Associate Director, Computational Biology: For a CRO (Frontage Laboratories, Inc. – Deerfield Beach, FL): lead the development, optimization and maintenance of computational pipelines for the analysis of next-generation sequencing (NGS) data in support of clinical and preclinical studies; collaborate with multidisciplinary teams to integrate sequencing-based assays including tumor profiling, germline analysis and cell-free DNA applications into routine workflows; design and implement scalable and reproducible bioinformatics tools using R, Python, and industry-standard platforms; partner with wet lab scientists to troubleshoot and refine high-throughput genomic workflows and ensure robust assay performance across diverse biological matrices; support validation and deployment of NGS-based assays into regulated production environments; provide scientific and strategic leadership on project design, data interpretation, and regulatory documentation for client-sponsored studies.

Requirements

• Master of Science or foreign equivalent degree in Biology, Computational Biology, Genomics or a related field.
• 3 years of experience in the job offered or 3 years of experience as a Computational Biologist. Experience must include genomic data interpretation, tumor profiling, germline variation, cell-free DNA and integration with qPCR or proteomic data, cloud-based computing (AWS, GCP), containerization (Docker/Singularity), and version control (Git) for scalable, reproducible workflows.
• Proficiency in Python, R and shell scripting.
• Experience using workflow engines (e.g., Nextflow, Snakemake, WDL/Cromwell).
• Knowledge of regulatory frameworks (CLIA, CAP, GLP) and assay validation processes in support of client-facing or clinical studies.

Responsibilities

• lead the development, optimization and maintenance of computational pipelines for the analysis of next-generation sequencing (NGS) data in support of clinical and preclinical studies
• collaborate with multidisciplinary teams to integrate sequencing-based assays including tumor profiling, germline analysis and cell-free DNA applications into routine workflows
• design and implement scalable and reproducible bioinformatics tools using R, Python, and industry-standard platforms
• partner with wet lab scientists to troubleshoot and refine high-throughput genomic workflows and ensure robust assay performance across diverse biological matrices
• support validation and deployment of NGS-based assays into regulated production environments
• provide scientific and strategic leadership on project design, data interpretation, and regulatory documentation for client-sponsored studies

What This Job Offers

• Job Type: Full-time
• Career Level: Director