Associate Director, Clinical Science

BioNTech • Cambridge, MA

1d

About The Position

As Associate Director, Clinical Science, you will be at the forefront of designing and executing oncology clinical trials that contribute to advancing BioNTech’s mission of developing innovative treatments. Your expertise will shape study designs and operational strategies, ensuring data integrity and compliance. Collaborating with cross-functional teams in a dynamic environment, you will drive impactful clinical trial processes while fostering excellence within the clinical science team. In this role, you will play a pivotal part in protocol development, trial execution, and engaging with scientific experts to inform clinical strategies. Your contributions will directly influence BioNTech’s goals and support robust medical governance across our programs.

Requirements

• Bachelor’s degree in life sciences or healthcare; advanced degree preferred with 8+ years of clinical experience is required; Master’s, PharmD, MPharm, PhD, MBBS, BDS, MD strongly preferred
• Proven experience in clinical development within oncology or immuno-oncology settings.
• Strong understanding of Good Clinical Practice (GCP) and all phases of drug development (Phase 1–3).
• Proficiency in planning and executing global clinical trials within pharmaceutical companies or CROs.
• Collaborative mindset with proven ability to work effectively in matrix environments and influence stakeholders without direct authority.
• Skilled in analyzing clinical data using tools like EDC platforms or Excel; experience in process optimization is desirable.

Responsibilities

• Lead protocol development and optimize clinical trial designs to assess investigational oncology drugs effectively.
• Collaborate with cross-functional teams to develop comprehensive clinical development plans aligned with program strategies.
• Drive execution of global clinical studies while ensuring adherence to protocols, regulatory standards, and ethical guidelines.
• Engage with internal and external scientific experts to interpret emerging data and incorporate best practices into trial conduct.
• Monitor study progress, review data trends, resolve adverse events, and ensure compliance throughout the study lifecycle.
• Mentor junior colleagues to cultivate a culture of continuous improvement within the clinical science team.

Benefits

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level