Associate Director, Cellular & Mechanistic Pharmacology

Johnson & Johnson • Spring House, PA

7d

About The Position

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: People Leader All Job Posting Locations: Spring House, Pennsylvania, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for an Associate Director, Cellular & Mechanistic Pharmacology located in Spring House, PA. Purpose: Translational Bioscreening is a newly formed team within the Multiomics Discovery function of Discovery Technologies & Molecular Pharmacology (DTMP). We contribute to the progression of cross-modality drug discovery projects from target identification to clinical development. Join our team! We’re looking for a talented scientific leader with an immunology background, deep expertise in disease biology and cellular pharmacology, and a passion for finding innovative therapeutics to treat diseases with high unmet medical need.

Requirements

• Ph. D. in Immunology, cell biology or equivalent with a minimum of 8 years of experience in a pharmaceutical industry setting developing and applying novel cellular assays is required.
• Proven track record in leading immunology-focused drug discovery programs across diverse modalities, in an industry setting.
• Deep expertise and proven accomplishments in de novo immunology cellular pharmacology assay development, complex immune cellular models and high-throughput technology platforms.
• Experience with generating and culturing translationally relevant cell models such as iPSC-derived cells, primary cells, and/or co-cultures.
• Expertise collecting and analyzing data using high dimensional approaches such as high content imaging, flow cytometry and/or RNAseq.
• Strong experience as a leader, problem solver and team collaborator able to facilitate understanding between biologists, chemists, and data scientists.
• A demonstrated ability to apply novel approaches to address complex biology questions, as evidenced through strong peer-reviewed publications.
• Excellent written communication, verbal communication, and oral presentation skills.
• Demonstrated influence, negotiation, and conflict resolution skills.

Nice To Haves

• Expertise in assay automation and analysis workflows.
• Proficiency with CAS/CRISPR, lentivirus and/or RNAi approaches.
• Expertise developing assays in translational and advanced cellular systems such as 3D models.
• Exposure to neuroscience and/or oncology therapeutic areas.
• Experience working with and/or guiding external collaborators in industry or academia.

Responsibilities

• Lead development of innovative cell-based assays for immunology-focused projects to identify and evaluate targets, and to progress hits and lead molecules.
• Act as a key liaison between DTMP and program teams, driving project strategy and execution, in partnership with cross-functional colleagues.
• Lead efforts to integrate translational and mechanistic biology with novel AI/ML methods to enable the discovery of novel therapeutics
• Manage and mentor a team of lab scientists.
• Analyze and present data at program team meetings, in-house seminars, leadership meetings and external scientific conferences, and publish research in high-quality journals.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees