Associate Director, Cell Pharmacology

Johnson & Johnson Innovative MedicineSpring House, PA
Onsite

About The Position

At Johnson & Johnson, health is everything. The company's strength in healthcare innovation empowers them to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through expertise in Innovative Medicine and MedTech, Johnson & Johnson is uniquely positioned to innovate across the full spectrum of healthcare solutions to deliver future breakthroughs and profoundly impact health for humanity. The Innovative Medicine sector is informed and inspired by patients, with teams working to develop medicines, find cures, and pioneer the path from lab to life while championing patients every step of the way. Translational Bioscreening is a newly formed team within the Multiomics Discovery function of Discovery Technologies & Molecular Pharmacology (DTMP). This team contributes to the progression of cross-modality drug discovery projects from target identification to clinical development. Johnson & Johnson is searching for a talented scientific leader with an immunology background, deep expertise in disease biology and cellular pharmacology, and a passion for finding innovative therapeutics to treat diseases with high unmet medical need.

Requirements

  • Minimum of Master’s Degree in Immunology, cell biology or equivalent with a minimum of 8 years of experience in a pharmaceutical industry setting developing and applying novel cellular assays is required.
  • Proven track record in leading immunology-focused drug discovery programs across diverse modalities, in an industry setting.
  • Deep expertise and proven accomplishments in de novo immunology cellular pharmacology assay development, complex immune cellular models and high-throughput technology platforms.
  • Experience with generating and culturing translationally relevant cell models such as iPSC-derived cells, primary cells, and/or co-cultures.
  • Expertise collecting and analyzing data using high dimensional approaches such as high content imaging, flow cytometry and/or RNAseq.
  • Strong experience as a leader, problem solver and team collaborator able to facilitate understanding between biologists, chemists, and data scientists.
  • A demonstrated ability to apply novel approaches to address complex biology questions, as evidenced through strong peer-reviewed publications.
  • Excellent written communication, verbal communication, and oral presentation skills.
  • Demonstrated influence, negotiation, and conflict resolution skills.

Nice To Haves

  • Expertise in assay automation and analysis workflows.
  • Proficiency with CAS/CRISPR, lentivirus and/or RNAi approaches.
  • Expertise developing assays in translational and advanced cellular systems such as 3D models.
  • Exposure to neuroscience and/or oncology therapeutic areas.
  • Experience working with and/or guiding external collaborators in industry or academia.

Responsibilities

  • Lead development of innovative cell-based assays for immunology-focused projects to identify and evaluate targets, and to progress hits and lead molecules.
  • Act as a key liaison between DTMP and program teams, driving project strategy and execution, in partnership with cross-functional colleagues.
  • Lead efforts to integrate translational and mechanistic biology with novel AI/ML methods to enable the discovery of novel therapeutics
  • Manage and mentor a team of lab scientists.
  • Analyze and present data at program team meetings, in-house seminars, leadership meetings and external scientific conferences, and publish research in high-quality journals.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Number of Employees

5,001-10,000 employees

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