Assoc. Scientist, Post Doc Fellow- Immunology, aging and neurodegenerative disease

Merck • Upper Gwynedd Township, PA

1d

About The Position

Postdoctoral Research Fellow –Immunology of aging and neurodegenerative disease
Our company is a global health care leader with a portfolio of prescription medicines, vaccines, and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
Be a part of the legacy: Research and Development Division Postdoctoral Research Fellow Program
The company's Research Laboratories Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Position Overview:
We are looking for an energetic, innovative postdoctoral fellow with strong expertise in immunology to join our team at the West Point, PA site.
You’ll become part of a highly collaborative research environment, working on a cross-functional project that bridges Immunology and Neuroscience.
In this role you will:
Design and execute mechanistic studies and develop relevant models to test hypotheses.
Work closely with mentors and a multidisciplinary team to shape research plans, generate robust data, and produce novel, field-advancing insights in neuroimmunology.
Launch and lead independent projects that investigate how adaptive immunity changes with aging and how these changes influence neurodegenerative disease.
If you are driven to translate curiosity into rigorously executed experiments and meaningful discoveries, this role offers the opportunity to make a significant impact at the interface of immunology and neuroscience.

Requirements

• Expertise in in vivo immunological response studies.
• Hands-on experience working with pre-clinical animal models and manipulating samples derived from these models.
• Hands-on experience and solid knowledge in aseptic techniques in tissue culture.
• Hands-on experience and solid knowledge in Immunology, molecular biology and cell biology.
• Hands-on experience with in vitro assay development and troubleshooting.
• Experience in immunological assays (e.g. ELISA, ELISPOT, high-parameter flow cytometry, cell sorting).
• Strong publication record and ability to design and execute experiments and interpret data.
• Excellent communication and collaboration skills.

Nice To Haves

• Experience in biochemistry/molecular biology assays (immunohistochemistry, western blot, Meso Scale Discovery assay et.al.)
• Familiarity or experience with single-cell omics assays and data analysis, in vitro restimulation assays.
• Familiarity or experience with Alzheimer’s disease animal models
• Familiarity or experience with vaccine platforms.

Responsibilities

• Establish and optimize models of innate and adaptive immune modulation in pre-clinical species.
• Develop immunological assays to characterize innate and antigen-specific humoral and cellular immune responses.
• Perform single cell assays including high-parameter flow cytometry and single cell omics profiling (e.g. single cell RNAseq and immune repertoire profiling).
• Perform neurodegenerative pathology analysis in animal models of disease using immunohistochemistry, western blot, company et.al.
• Data interpretation, manuscript and patent preparation, publication, and presentation.

Benefits

• Our company's benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives.
• Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree