Assistant Research Scientist - Rodent Genome Engineering Lab

NYU Langone Medical Center•New York, NY

43d•Onsite

About The Position

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the Grossman School of Medicine at its core is committed to improving the human condition through medical education, scientific research, and direct patient care. At NYU Langone Health, equity and inclusion are fundamental values. We strive to be a place where our exceptionally talented faculty, staff, and students of all identities can thrive. We embrace inclusion and individual skills, ideas, and knowledge. For more information, go to med.nyu.edu, and interact with us on LinkedIn, Glassdoor, Indeed, Facebook, Twitter and Instagram. Position Summary: We have an exciting opportunity to join our team as a Assistant Research Scientist - Rodent Genetic Engineering Laboratory. The Rodent Genome Engineering Lab (RGEL) at NYU Langone Health is seeking an Assistant Research Scientist to expand its transgenic model services. This onsite role focuses on generating complex genomically engineered mouse models in close collaboration with Dr. Jef Boeke at the Institute for Systems Genetics (NYULH). The Assistant Research Scientist will report to RGEL's Associate Director. Key responsibilities include executing research projects to produce genomically engineered mice using mouse embryonic stem cell (mESC) chimeric blastocyst microinjection and embryo transfer. The role involves mESC culture, blastocyst injection, rederivation, cryopreservation, in vitro fertilization, and sperm cryopreservation. The scientist will also maintain breeding colonies and detailed records. The ideal candidate will perform both routine and advanced laboratory techniques, contribute to method development, and uphold high-quality standards in transgenic support services. The position requires independent planning and execution of experiments, animal model management, and timely completion of assigned projects. RGEL operates as a fee-for-service core facility, providing innovative resources to biomedical researchers. The Assistant Research Scientist will work within this collaborative core environment, supporting its mission and partnering with principal investigators who utilize the labs services.

Requirements

To qualify you must have a MS degree in a related discipline and 0-1 year of experience or equivalent combination of education and experience.
Qualified candidates must be able to effectively communicate with all levels of the organization.

Nice To Haves

Education: Masters degree (M.A/B.S) is preferred.
Experience: 2 years of laboratory animal experience in an AAALAC accredited transgenic core facility is required. Direct experience with mouse microinjection procedures is preferred. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

Responsibilities

Independently generate chimeric mice for service projects designed by the principal investigators, including all scheduling, animal handling, microinjection, and associated tasks.
Work with RGELs Director and Associate Director, as well as with Dr. Boeke to develop enhanced methods and protocols for transgenic mouse generation.
Document progress and generate timely reports and presentations.
Independently perform mouse rederivation, including sperm cryopreservation.
Independently perform mouse handling tasks, including hormone injection (PMSG, HCG), superovulation, mating, and weaning.
Independently perform euthanasia of mice and collection of blastocysts or zygotes.
Independently inject mouse embryonic stem cells into mouse blastocysts to generate chimeric mice.
Independently perform rederivation of mouse strains to specific pathogen-free status.
Independently perform embryo oviduct transfer.
Monitor daily animal health and welfare.
Demonstrates knowledge of the organizations core values and incorporates them into the performance of duties.
Maintain required attendance level and adherence to the work schedule in accordance with the required staffing levels to ensure that assigned duties are completed.
Responsible for the maintenance and upkeep of all instruments and laboratory facilities, core laboratory procedures and practices, including quality control and compliance.
Performs other related duties as assigned.
Maintain confidentiality of all research information
Excel in cooperation, collaboration and communication with all NYULH employees
Communicate professionally and precisely with other team members and clients
Is able to recognize problems as they occur, and through the application of appropriate policy/procedure, determines and/or recommends the appropriate solution. Must be able to troubleshoot.
Seeks guidance as necessary for the performance of duties; asks appropriate questions when in doubt and utilizes reference sources/materials to ensure accuracy.
Advises appropriate personnel of situations/problems requiring intervention or follow-up attention.

Benefits

NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents.
At NYU Langone Health, we are committed to supporting our workforce and their loved ones with a comprehensive benefits and wellness package.
Our offerings provide a robust support system for any stage of life, whether it's developing your career, starting a family, or saving for retirement.
The support employees receive goes beyond a standard benefit offering, where employees have access to financial security benefits, a generous time-off program and employee resources groups for peer support.
Additionally, all employees have access to our holistic employee wellness program, which focuses on seven key areas of well-being: physical, mental, nutritional, sleep, social, financial, and preventive care.
The benefits and wellness package is designed to allow you to focus on what truly matters.
Join us and experience the extensive resources and services designed to enhance your overall quality of life for you and your family.

Stand Out From the Crowd

Upload your resume and get instant feedback on how well it matches this job.

Upload and Match Resume