Analytical Development Research Scientist

Vertex Inc. • Boston, MA

5d • Onsite

About The Position

General summary: Vertex is seeking a talented scientist to join our small molecules Analytical Development group in Boston, MA. This individual will play a central role in advancing transformative medicines by leading select analytical chemistry activities to support small molecules, oligonucleotides, peptides, lipid nanoparticle (LNP)–based formulations and conjugated therapeutics development programs from preclinical through to Phase 1. This role includes active participation in cross‑functional project team meetings, working collaboratively with other R&D functions to resolve project challenges. The ability to work both independently and in a matrix team environment is essential to succeed in this position.

Requirements

• The ability to work successfully in both a team/matrix environment as well as independently
• Experience developing and applying analytical methods to support formulation development and characterization, including particle‑based or lipid-based delivery systems
• Strong troubleshooting skills and problem-solving capabilities
• Strong analytical data assessment, review and interpretation skills
• Demonstrated experience in communication of technical data: writing reports and presentation skills
• High attention to detail
• Ability to work in a fast-paced environment, managing priorities and maintaining timelines
• Ph.D. (or equivalent degree) and 0-3 years of relevant post-doctoral employment experience, or Masters Degree (or equivalent degree) and 3+ years of relevant employment experience, or Bachelors Degree (or equivalent degree) and 6+ years Relevant professional analytical development experience in the pharmaceutical industry

Nice To Haves

• Technical expertise in analytical techniques supporting LNP and particle-based formulation characterization (e.g., LC-CAD, SEC-MALS, DLS, NTA, zeta potential), with additional experience in small‑molecule analytical methods considered a plus

Responsibilities

• Project oversight: participate in and support cross-functional teams and effectively communicate issues and solutions to colleagues at all levels within the organization
• Strategy: contributes to the development, alignment and execution of analytical project team plans and strategies to support drug substance and drug product development including formulation‑relevant analytical method development, stability, physicochemical characterization, and validation activities
• Laboratory expertise: apply hands‑on analytical skills and understanding in laboratory techniques routinely used in the analysis of drug substance, formulated drug product, and lipid‑based or particle‑based delivery systems
• Collaboration: work both independently and collaboratively within a matrix team environment
• Communication: demonstrated ability to effectively present results in both oral and written reports and to productively disseminate ideas across discipline and project boundaries
• Continuous improvement: develop, contribute, and support improvements in analytical workflows, processes, and ways of working that improve productivity, efficiency, and overall effectiveness

Benefits

• At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
• From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level