Analytical Chemist (Contract)

Vertex PharmaceuticalsBoston, MA
5d$65 - $75

About The Position

The Analytical Chemist will join Vertex’s growing Technical Operations Analytical team and has the primary responsibility to provide analytical support for Oligonucleotides and Peptides in late-stage phase.

Requirements

  • MS or BS with 5+ years of industrial experience
  • Strong background in analytical development and validation of methods for analysis of oligonucleotide therapeutics
  • Strong knowledge of mass spectrometry and purification techniques
  • Knowledge of cGMP’s
  • Must be a committed team player and collaborator

Nice To Haves

  • Knowledge in RP-HPLC, SAX-HPLC, UPLC, LC-MS is preferred.

Responsibilities

  • Primary responsibility to provide analytical support for Oligonucleotide and Peptide-Oligonucleotide conjugated compounds
  • Development and optimization of robust LC/MS, IPRP and SAX HPLC analytical methods for analysis and purification of highly modified oligonucleotide drug substances
  • Experience with IP-RP-HPLC, AX-HPLC, UPLC, LC-MS, LC-MS/MS analytical techniques using Agilent, Waters and/or Thermo’s and associated software
  • Operate, maintain and troubleshoot lab instruments
  • In depth knowledge of GLP/GMP’s in a pharmaceutical environment
  • Must possess excellent writing and communication skills and a demonstrated ability to work independently and with cross-functional teams
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