Eli Lilly-posted 10 months ago
$121,500 - $198,000/Yr
Full-time • Entry Level
Indianapolis, IN
Chemical Manufacturing

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $121,500 - $198,000. This position is part of the Upstream Process Development group in the Bioprocess Research and Development (BR D) organization within Lilly Research Labs. BR D delivers new medicines to patients through the development and commercialization of insulins, peptides, oligonucleotides, monoclonal antibodies, novel therapeutic proteins, and gene therapy systems. The Advisor - Upstream Process Development is responsible for the development and optimization of cell lines, strains, technology and processes for production of recombinant therapeutic proteins and genetic medicines, as well as for process control strategy development, process scale-up and technology transfer to pilot plant and manufacturing sites.

  • Lead the design, execution, and interpretation of upstream experiments for processes leading to the generation of drug substance (therapeutic proteins or genetic medicines).
  • Participate in and/or lead cross-functional process development teams, and effectively collaborate with other groups in Bioprocess and Bioproduct Development, Discovery, TS&MS and Manufacturing.
  • Support transfer of upstream processes to manufacturing sites.
  • Use mathematical methods and computer tools to model and explore experimental systems.
  • Authorship of technical reports and regulatory documents.
  • Work effectively with external parties on development projects, research collaborations and outsourcing efforts.
  • Lead/support implementation of organizational strategic initiatives in support of the Lily pipeline.
  • Keep abreast of relevant scientific literature/new technologies/capabilities and regulatory initiatives/requirements.
  • Leverage internal and external influence to solve problems and benchmark potential solutions.
  • Provide coaching, training, and administration of performance management to personnel (primarily, but not limited to, direct reports).
  • Ensure work and team activities are aligned with all relevant Development Quality, regulatory, HSE, GLP and requirements.
  • Ph.D. in Chemical Engineering, Biochemistry, Biology, Bioengineering or related field; alternatively, skills commensurate with a PhD scientist with 0-3 years of experience.
  • General knowledge of cell culture, molecular biology and fermentation with an emphasis on production of recombinant proteins and genetic medicines.
  • General knowledge and understanding of issues associated with scaling of upstream processes, and use of statistics for data analysis.
  • Cell culture experience with CHO or HEK293 cell lines.
  • Problem solving and decision-making.
  • Demonstration of scientific and people leadership skills.
  • Effective oral and written communication skills.
  • Must be able to work productively in an interdisciplinary team environment.
  • Eligibility to participate in a company-sponsored 401(k); pension.
  • Vacation benefits.
  • Eligibility for medical, dental, vision and prescription drug benefits.
  • Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts).
  • Life insurance and death benefits.
  • Certain time off and leave of absence benefits.
  • Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
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