Advisor / Sr. Advisor, Mass Spectrometry-based Biomarker Discovery - Neuroscience

Eli Lilly and CompanyBoston, MA
2d$138,000 - $224,400Onsite

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Development and validation of novel mass spectrometry-based assays for early- and late-phase clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders. Work with project team leads, including Dr. Kaj Blennow (Vice President of Neuroscience Biomarker Development), the Director for mass spectrometry-based biomarker discovery, and other associates to perform experiments to support both the preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development. Work directly on-site in the laboratory with method development, optimization, and sample analyses, and with summarizing and reporting method status of results for internal partners. Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses. Collaborate cross-functionally with internal stakeholders (medical, operations, statistics, regulatory) and external partners (CROs, academic institutions) to ensure biomarker validation and successful integration into clinical programs

Requirements

  • PhD in Biology, Biochemistry, Neuroscience, or related scientific discipline with 3+ years industry, academic, or postdoctoral experience.
  • Must have an understanding of the mass spectrometry technology and instrumentation as well as documented hands-on experience in mass spectrometry-based assay development and validation for biomarker applications in clinical diagnostics, clinical trials, or preclinical sample analysis.
  • Must be technically skilled to in the field of mass spectrometry-based analyses as well as immunoprecipitation, database searches.
  • Excellent communication and collaboration skills, with the ability to present to influence both internal and external stakeholders.

Nice To Haves

  • Experience in label-based quantificatiuon (TMT/iTRAQ) is a merit.

Responsibilities

  • Development and validation of novel mass spectrometry-based assays for early- and late-phase clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders.
  • Work with project team leads, including Dr. Kaj Blennow (Vice President of Neuroscience Biomarker Development), the Director for mass spectrometry-based biomarker discovery, and other associates to perform experiments to support both the preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development.
  • Work directly on-site in the laboratory with method development, optimization, and sample analyses, and with summarizing and reporting method status of results for internal partners.
  • Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses.
  • Collaborate cross-functionally with internal stakeholders (medical, operations, statistics, regulatory) and external partners (CROs, academic institutions) to ensure biomarker validation and successful integration into clinical programs

Benefits

  • Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
  • Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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