About The Position

Takeda’s QCP & PMX is an integral part of the broader Quantitative Pharmacology & Translational Sciences organization within the R&D Data and Quantitative Sciences unit. The mission of QCP and PMX is to globally advance therapeutics by finding the right dose for the right patients with a purpose of maximizing benefit over risk. The model-based meta-analysis (MBMA) is crucial to enhance decision-making in the clinical development of multiple internal assets within Takeda’s Oncology therapeutic area. In this role, the QCP & PMX intern will establish a MBMA framework for predicting long-term outcomes (OS/PFS) from the short-term endpoints (ORR, CR, PR etc.) to support early go/no-go decisions and improve future clinical trial designs.

Requirements

  • Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship
  • Must be currently enrolled in a degree program graduating December 2026 or later
  • The internship program is 10- 12 weeks depending on the two start dates ( May 26 th -August 14 th or June 15 th - August 21 st )
  • The intern must be able to commit to one of these time frames
  • Able to work full time 40 hours a week during internship dates
  • This position will be hybrid in the Cambridge office.
  • The candidate must be pursuing a PhD in Pharmaceutical Sciences, Clinical Pharmacology, Pharmacometrics, Biostatistics, or another relevant field (Candidates with applied projects in Clin Pharm/PMx during their senior Ph.D. years with prior internship experience are preferred).
  • Demonstrate an understanding of basic concepts in PK/PD and biostatistics.
  • Be acquainted with standard techniques of model building, validation, and simulations.
  • Be motivated to conduct hands-on analyses in the context of clinical drug development with the ultimate goal of bringing back useful insights into the drug-development teams who do not have this kind of background.

Nice To Haves

  • Experience in using R/Rstudio software is a plus.

Responsibilities

  • Literature review: Latest publications & MBMA methodology.
  • Building a comprehensive database for conducting hands-on analyses.
  • Model building (link short-term endpoints to PFS/OS) and validation.
  • Conducting head-to-head clinical trial simulations.
  • Benchmarking Takeda’s internal assets against SoC/external competitors in early development and inform clinical development plan within the oncology space.

Benefits

  • Paid sick time
  • Civic Duty paid time off
  • Participation at company volunteer events
  • Participation at company sponsored special events
  • Access to on-site f itness c enter (where a vailable )
  • Commuter Benefit: To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking.

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What This Job Offers

Job Type

Full-time

Career Level

Intern

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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