2026 Summer Intern - Translational Safety (Investigative Toxicology)

Roche • South San Francisco, CA

4d • $33 - $46 • Onsite

About The Position

2026 Summer Intern - Translational Safety (Investigative Toxicology) Department Summary Development Sciences (DevSci) spans the entire drug discovery and development cycle — from early stage research to drug commercialization. Part of the drug development pipeline in DevSci includes the preclinical safety evaluation of candidate therapeutic molecules by toxicologists and pathologists in the Translational Safety (TS) department in order to enable further evaluation in humans. We are also committed to providing better outcomes for our people, patients, business, and communities by advancing and boldly championing diversity, equity, and inclusion in our work. Translational Safety’s Vision and Mission: We revolutionize and accelerate drug development through cutting-edge predictive, translational sciences. We develop transformative therapeutics for patients by delivering rigorous translational strategies and model-informed predictive insights for all therapeutic modalities through the entire drug development lifecycle via innovative experimental and computational approaches. The summer intern will join Genentech's Investigative Toxicology group. The role requires proficiency in cell culture and molecular biology for assay development, mechanistic studies, and applying novel in vitro methodologies for Translational Safety. A primary focus is advancing predictive models for drug-induced lung disease (DILD). This internship position is located in South San Francisco, on-site. The Opportunity: Join our dynamic research team as a summer intern and gain valuable hands-on experience while contributing to meaningful advancements in Translational Safety. This role offers a unique opportunity to develop and apply scientific skills in a cutting-edge research environment, working with state-of-the-art technologies that drive progress in drug safety and development. Ideal for candidates eager to embrace innovative methodologies and expand their expertise in a collaborative and stimulating setting. As a key member of our team, you will play a vital role in establishing, qualifying, and implementing advanced technologies and platforms to support safety assessment efforts, including: Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.

Requirements

• You meet one of the following criteria: Must have attained a Bachelor's Degree (recent graduate). Must be pursuing a Master's Degree (enrolled student). Must have attained a Master's Degree (recent graduate). Must be pursuing a PhD (enrolled student).
• Required Majors: Life Sciences, Biology, Toxicology, Bioengineering, Biochemistry, Chemistry, Pharmacology, Cellular or Molecular Biology, Genetics or a related field.
• Proven ability to independently design, troubleshoot, and conduct experiments, interpret data, and solve problems.
• Prior hands-on wet lab experience, including but not limited to technical skills such as calculating molarity and accurate pipetting.
• Experience in assay development/ optimization.
• Ability to professionally present research to lab groups and departments using effective presentation tools.
• Eagerness to learn about the end-to-end drug development process, including non-clinical (animal) studies.
• Excellent organizational skills, attention to detail, and adaptability to a dynamic research environment.
• Demonstrated enthusiasm for building a meaningful career in drug discovery and safety sciences.

Nice To Haves

• Excellent communication, collaboration, and interpersonal skills with a proactive desire to support and work closely with colleagues.
• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
• Experience with high-content imaging methodologies specifically for toxicology applications.
• Advanced proficiency in Python (or other coding languages) for data manipulation and development of analysis pipelines.
• Expert knowledge in lung biology and its application to relevant research.
• Authorship of manuscripts (published or preprints) showcasing rigorous scientific research.
• Evidence of professional communication skills through conference presentations, including oral talks and/or poster presentations.

Responsibilities

• Advancing 3D and microphysiological systems.
• Applying iPSC-derived cell models for diverse safety-focused studies.
• Utilizing live-cell and high-content imaging techniques (e.g., cell painting) to enhance predictive toxicity assessments.
• Implementing high-content imaging methodologies for predictive safety evaluations.
• Developing and optimizing cross-species in vitro models to bridge translational gaps and improve relevance to human biology.

Benefits

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.
• This position also qualifies for paid holiday time off benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Number of Employees: 5,001-10,000 employees