2026 Summer Intern - Enzyme Technologies Chapter
About The Position
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position 2026 Summer Intern - Enzyme Technologies Chapter We advance science so that we all have more time with the people we love. The Enzyme and Protein Engineering (EPE) team is seeking a highly motivated intern to join our team with a primary focus on experimental protein science, computational protein analysis, and post-translational modifications (PTMs). This position offers hands-on laboratory experience in protein characterization and analytical techniques, combined with computational modeling and in-silico protein design. The successful candidate will work at the bench performing protein analytics, support enzyme engineering through computational predictions and molecular dynamics simulations, and contribute to the organization and automation of experimental data, helping to bridge laboratory science with computational analysis and data management systems. This internship position is located in Santa Clara, California, on-site.
Requirements
- Must be pursuing a Bachelor's Degree (enrolled student)
- Must be pursuing a Master's Degree (enrolled student).
- Must be pursuing a PhD (enrolled student).
- Biochemistry, Molecular Biology, BioEngineering, Bioinformatics, Computer Science, Data Science, or related field
- Strong interest in protein sciences and post-translational modifications
- Proficiency in Python and/or R for data analysis and automation
- Basic understanding of protein structure and function
- Excellent problem-solving and analytical skills
- Strong communication skills and ability to work in cross-functional teams
Nice To Haves
- Prior laboratory experience in protein biochemistry or analytical chemistry
- Prior experience in NGS sequencing applications and or data analysis
- Familiarity with chromatography principles and mass spectrometry data formats
- Experience with protein computational tools: Protein large language models (ESM, ProteinMPNN, AlphaFold), Molecular dynamics simulation packages (GROMACS)
- Experience with automation tools and frameworks: API development (FastAPI), database management (SQL), Cloud platforms (BigQuery)
Responsibilities
- Assist with the design, expression, and purification of recombinant proteins - ELISA/SDS-PAGE/HPLC/Western Blot Etc.
- Investigations of post-translational modifications such as glycosylation, phosphorylation, acetylation, and Ubiquitination using fluorescence based and MassSpec based assays
- Assist with rational protein structure predictions utilizing molecular dynamic simulations and protein language models (GROMACS/ProtBERT)
- Assist in developing tools for high-throughput data extraction, transformation, and storage
Benefits
- Intensive 12-week, full-time (40 hours per week) paid internship.
- Program start dates are in May/June (Summer).
- A stipend, based on location, will be provided to help alleviate costs associated with the internship.
- Ownership of challenging and business-critical projects.
- Work with some of the most talented people in the biotechnology industry.
- paid holiday time off benefits
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
5,001-10,000 employees
