2026 Summer Intern - Drug Metabolism and Pharmacokinetics – Metabolomics

Genentech•Daly City, CA

13h•$40 - $46•Onsite

About The Position

The Drug Metabolism and Pharmacokinetics (DMPK) Department at Genentech Research and Early Development (gRED) has a vision to advance the development of safe and efficacious life-changing therapeutics for patients as an integral partner. The Metabolomics and Lipidomics Group under Bioanalysis Function supports research biology, drug discovery and development across Genentech by generating high-quality metabolomics and lipidomics data through the use of state-of-the-art technologies and high-throughput workflows and deciphering biochemical insights for target assessment and biomarker discovery. This internship position is located in South San Francisco CA, on-site. The candidate will support the development and evaluation of quantitative assays for global metabolomics by using various liquid chromatography-mass spectrometry (LC-MS) instruments and data processing tools. This position provides an opportunity to significantly advance cutting-edge metabolomics workflows and impact on enhancing reproducibility and standardization of metabolomics assay for research and drug discovery projects.

Requirements

Must be pursuing a Master's Degree (enrolled student).
Must be pursuing a PhD (enrolled student).
Required Majors: Chemistry (Analytical Chemistry), Biochemistry, Pharmaceutical Science, Biomedical Sciences, Biomedical Engineering, or related fields.
Hands-on experience with sample preparation techniques and LC-MS with a focus on metabolomics, lipidomics, or small-molecule bioanalysis.
Proficiency in processing metabolomics MS raw data and quantitative analysis.
Experience in R or Python for data analysis and visualization.
Team collaboration and the ability to work independently.

Nice To Haves

Prior experience with studying cellular and/or organismal metabolism is a plus.
Excellent communication, collaboration, and interpersonal skills.
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

Implement and assess different analytical strategies to build a quantitative metabolomics assay for common biological matrices.
Establish and apply QC metrics to evaluate accuracy, precision, sensitivity, reproducibility, and robustness of the assay.
Standardize and automate data analysis workflow to streamline quality check and expand throughout while maintaining high quality.
Incorporating the quantitative workflow into project support for in-house studies.

Benefits

Intensive 12-weeks, full-time (40 hours per week) paid internship.
Program start dates are in May/June, 2026.
A stipend, based on location, will be provided to help alleviate costs associated with the internship.
Ownership of challenging and impactful business-critical projects.
Work with some of the most talented people in the biotechnology industry.
Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions.
paid holiday time off benefits

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