2026 Summer Intern - Cell Therapy

Roche•South San Francisco, CA

7d•$46 - $46•Onsite

About The Position

The Cell Therapy Department in gRED (Genentech Research and Early Development) is seeking a talented graduate student to help develop cutting-edge cell therapies. The successful candidate for this laboratory-based position will work closely with our scientists to lead a discovery project to develop and enhance T cell therapy platforms. Our department fosters an open, collaborative environment where everyone’s contribution helps us deliver innovative cell therapies to the clinic. This internship position is located in South San Francisco, on-site. The intern will be responsible for a range of activities, which may include: Lead an independent project evaluating different genetic engineering strategies on T cells and iPSC-derived T cells. Use different tools to introduce novel constructs into T cells and iPSCs and evaluate impact on T cell phenotype and function. Phenotype T cells for subset, activation, and exhaustion markers using flow cytometry and other methods. Analyze data using FlowJo and Prism/R/Python to extract insights and frame additional lines of inquiry. Present experimental designs, analysis strategies, and results in group and department meetings, as well as at final Intern Symposium. Intensive 12-week full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.

Requirements

Must be pursuing a PhD (enrolled student).
Immunology, Cancer Biology, Genetics/Genomics, Cell Biology, or related field.
Extensive experience culturing and engineering primary T cells with lentivirus, nucleases, and/or other genome editing techniques.
Hands-on experience designing and running multi-parameter flow cytometry panels.
Proficiency with molecular biology assays and NGS workflows.
Deep understanding of T cell and CAR-T biology, with knowledge of TCR signaling, cytokine signaling, and thymic development.
Ability to design experiments and troubleshoot independently.

Nice To Haves

Experience culturing and engineering iPSCs.
Experience differentiating iPSCs to T cells is a plus.
Familiarity with in vitro assays and in vivo models for oncology and autoimmune CAR-T applications.
Excellent communication, collaboration, and interpersonal skills.
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

Lead an independent project evaluating different genetic engineering strategies on T cells and iPSC-derived T cells.
Use different tools to introduce novel constructs into T cells and iPSCs and evaluate impact on T cell phenotype and function.
Phenotype T cells for subset, activation, and exhaustion markers using flow cytometry and other methods.
Analyze data using FlowJo and Prism/R/Python to extract insights and frame additional lines of inquiry.
Present experimental designs, analysis strategies, and results in group and department meetings, as well as at final Intern Symposium.