2026 Summer Intern - Analytical Development (Molecular Biology)

Roche • Philadelphia, PA

2d • $23 - $35 • Onsite

About The Position

The Analytical Development team in Philadelphia is part of Roche’s Gene Therapy technical development function (PTCG); building the roadmap for product safety and efficacy. By characterizing viral capsids, we provide the data that brings life-changing medicines to patients. Our Molecular Biology group is seeking a motivated Co-op to advance AAV analytical capabilities. You will develop advanced methods for residual DNA characterization, offering a unique opportunity to apply molecular biology expertise to a high-value, GxP-supporting analytical project. This internship position is located in Philadelphia, on-site.

Requirements

• Currently pursuing a Bachelor's or Master's degree in Molecular Biology, Biochemistry, Analytical Chemistry, or a related life science field.
• Hands-on experience with fundamental nucleic acid handling and molecular techniques (e.g., standard PCR, qPCR, gel electrophoresis).
• Demonstrated proficiency in basic laboratory techniques, including meticulous pipetting and solution preparation.
• Proficiency in data processing and analysis using tools such as Microsoft Excel, with an ability to interpret complex quantitative data.
• Excellent communication, organizational, and collaboration skills, with a passion for problem-solving.
• You meet one of the following criteria: Must be pursuing a Bachelor's degree. Must have attained a Bachelor's degree (recent graduates not currently enrolled in a grad program). Must be pursuing a Master's degree.
• Required Majors: Chemistry, Genetics, Biology, Biochemistry, Molecular Biology, Pharmaceutical Sciences, or related fields.
• Practical experience with Molecular Biology related lab techniques and safety.
• Strong academic understanding of nucleic acid handling, PCR/QPCR, and gel electrophoresis.

Nice To Haves

• Excellent communication, collaboration, and interpersonal skills.
• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
• Familiarity with gene therapy concepts or Adeno-Associated Virus (AAV) biology.
• Theoretical understanding or exposure to nucleic acid quantification methods, specifically PCR/qPCR/dPCR.

Responsibilities

• Gain hands-on experience with Digital PCR (dPCR) workflows- alongside other molecular biology techniques to characterize viral vector residual DNA.
• Work alongside Subject Matter Experts (SMEs) to design and execute wet-lab experiments and conduct initial method pre-qualification studies.
• Analyze experimental data to assess the size of residual DNA impurities, contributing to the team’s understanding of product quality.
• Document experimental protocols and results in laboratory notebooks and present technical findings to the research team.
• Collaborate with senior scientists to integrate the final quantitative dPCR assay into the existing Molecular Biology platform.

Benefits

• Intensive 6 months, full-time (40 hours per week) paid internship.
• Program start dates are in May/June 2026.
• A stipend, based on location, will be provided to help alleviate costs associated with the internship.
• Ownership of challenging and impactful business-critical projects.
• Work with some of the most talented people in the biotechnology industry.
• This position also qualifies for paid holiday time off benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Number of Employees: 5,001-10,000 employees