2026 Summer Intern - Agents for Structural Biology
About The Position
The Department of Structural Biology at Genentech is seeking talented graduate students with experience in structural biology and agentic systems for the 2026 Genentech Summer Intern Program. The interns will help build and develop an agentic system for assisting in experimental structural biology data processing and analysis to increase automation and throughput. The interns will gain experience in some or all of the following areas: scientific programming, structural biology data processing, agentic systems, prompt/context engineering, and Model Context Protocol (MCP) tools. Our department offers a highly interdisciplinary environment for drug discovery and biomedical research, with state-of-the-art resources and unparalleled opportunities for scientific collaboration. We integrate macromolecular crystallography, cryoEM, and NMR spectroscopy to drive drug discovery and uncover fundamental biology. We explore the structural and functional properties of proteins of therapeutic interest and their interactions with diverse ligands. We collaborate with scientists throughout Genentech to advance discovery of drugs (small molecule, proteins, antibodies, peptides, nucleotides, etc.), as well as to pursue basic research questions regarding protein structure and function. This internship position is located in South San Francisco and the intern is expected to be on site.
Requirements
- Must be pursuing a Master's Degree (enrolled student). Must have attained a Master's Degree. Must be pursuing a PhD (enrolled student).
- Biophysics, Structural Biology, Biochemistry, Chemistry, Computer Science, Data Science, Systems Biology, Mathematics, Statistics, or related disciplines
- Experience solving x-ray crystal and/or cryoEM structures from data processing to model building
- Proficient python programmer
- Familiarity with agentic coding tools and MCP clients like Cursor or Claude Code
Nice To Haves
- Experience building Model Context Protocol (MCP) tools
- Experience with prompt/context engineering
- Excellent communication, collaboration, and interpersonal skills
- Behavior consistent with our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
- Curious, quick and resourceful learner
- Innovative thinking to solve challenging scientific and technical problems.
Responsibilities
- Develop MCP tools for structural biology data processing
- Build custom prompts to provide context for structural biology domain knowledge
- Test and optimize prompts and tools for automating structural biology data processing workflows
- Develop a testing framework to ensure reliable and robust performance
- Produce training materials for structural biology scientists
Benefits
- Intensive 12-weeks, full-time (40 hours per week) paid internship.
- Program start dates are in May/June (Summer).
- A stipend, based on location, will be provided to help alleviate costs associated with the internship.
- Ownership of challenging and impactful business-critical projects.
- Work with some of the most talented people in the pharmaceutical/biotechnology industry.
- paid holiday time off benefits
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
5,001-10,000 employees
