Scientist

Astrix TechnologyBoston, MA
411d$52,000 - $56,160

About The Position

The Histology Scientist will be part of the In Vivo Pharmacology - Oncology group, focusing on advancing novel therapeutics through histology and immunohistochemistry experiments. This role involves managing tissue samples, conducting quantitative image analysis, and collaborating with cross-functional teams to support project objectives.

Requirements

  • Associate/BS/BA/Master's degree with at least 1 year of relevant experience in histology or a related scientific field.
  • Expertise in processing, embedding, and sectioning FFPE tissues.
  • Experience performing immunohistochemistry (IHC) and familiarity with immunofluorescence (IF) and RNAscope assays.
  • Proficiency in image acquisition and interpretation for quality assessment.
  • Familiarity with automated immunostainers (e.g., Leica Bond, Ventana), and experience with Laboratory Information Management Systems (LIMS) is desirable.
  • Exposure to quantitative image analysis tools such as ImageJ, Indica Labs HALO, or QuPath is a plus.
  • Interest or background in oncology, immune-oncology, and/or immunology is preferred.

Nice To Haves

  • Familiarity with automated immunostainers (e.g., Leica Bond, Ventana).
  • Experience with Laboratory Information Management Systems (LIMS).
  • Exposure to quantitative image analysis tools such as ImageJ, Indica Labs HALO, or QuPath.

Responsibilities

  • Design, validate, and execute IHC and histology experiments on human and mouse tissue samples.
  • Utilize Indica Labs HALO Link for managing images and processing digital pathology data, including manual data entry.
  • Conduct quantitative image analysis using Indica Labs HALO AI to support data interpretation and validation.
  • Collaborate with cross-functional teams to communicate experimental findings and support project objectives.
  • Independently manage project timelines and execute tissue-based assays to ensure timely completion of experiments.
  • Maintain a meticulous electronic lab notebook (ELN) and participate in training sessions to ensure compliance with best practices.
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