Research Associate, Infectious Disease (Arias Group - Biohub SF)

Chan Zuckerberg Biohub - San Francisco • San Francisco, CA

313d • $52,000 - $77,000

About The Position

The Arias Group at the Chan Zuckerberg Biohub is looking for a curious, energetic, passionate, and talented Research Associate to join us. We are interested in exploring the mechanisms used by viruses to hijack the protein synthesis machinery. Our ultimate goal is to identify factors required for viral replication but dispensable for normal cell function that could be exploited to develop new antiviral strategies. Our primary research will evaluate the antiviral target potential of previously identified factors and establish methods to identify new candidate targets, including CRISPR-based screens and Ribosome Profiling.

Requirements

• Bachelor's degree in a life science or associated field with relevant coursework including molecular biology, cell biology, biochemistry and microbiology/virology
• Minimum of 1 year of experience with wet laboratory techniques (DNA and RNA isolation, PCR, cloning/construct design)
• Hands on tissue culture experience
• Familiarity with gene manipulation and expression analysis methods (gene overexpression and stable expression, RNAi, CRISPR, qPCR, sequencing)
• Familiarity with protein tagging, expression and purification processes
• Experience in data collection, analysis, and interpretation
• Attention to detail and very strong organizational skills
• Excellent written and verbal communication skills
• Ability to multi-task and work both independently and collaboratively across platforms

Nice To Haves

• Master’s degree in life sciences or related field
• Experience working with viruses
• 3 years experience in molecular lab techniques (qPCR, protein purification, tissue culture, cytometry, microscopy)
• Previous research, job or internship experience in an academic or industry setting involving one year of tissue culture experience.
• Experience with proteomics and transcriptomics
• Experience with drug screens

Responsibilities

• Under the mentorship and supervision of senior researchers, plan and carry out experiments designed to understand host and virus dynamics during an infection
• Create and maintain a library of cell lines as needed for various studies
• Learn and utilize cutting edge techniques involving microscopy, flow cytometry, mass spectrometry, CRISPR, drug screens and high throughput sequencing
• Work with personnel from different research platforms (proteomics, genomics, imaging, cell biology, data science)
• Troubleshoot protocols, maintain detailed records, analyze results, and contribute ideas to research projects

Benefits

• Healthcare coverage
• Life and disability insurance
• Commuter subsidies
• Family planning services with fertility care
• Childcare stipend
• 401(k) match
• Flexible time off
• Generous parental leave policy

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Bachelor's degree