2025 Summer Intern - gRED, Regev Lab

Genentech • South San Francisco, CA

362d • $50

About The Position

The 2025 Summer Intern position is located in South San Francisco, on site, within the Regev Lab at Genentech. This internship focuses on cellular deconvolution, a technique used to infer the unknown composition of bulk RNAseq samples. Traditionally, this method has been limited to estimating abundances of discrete cell types. However, recent approaches utilizing maximum entropy models and generative models show promise in inferring continuous processes such as differentiation. The Regev lab aims to develop a deep generative model that builds on these approaches, trained on extensive and heterogeneous reference atlases containing tens of millions of single cells from hundreds of studies. This model will facilitate the routine profiling of large volumes of bulk RNAseq data collected in-house, with an assessment of its accuracy in epithelial, cancer, and other tissue samples containing diverse and continuous cell states.

Requirements

• Must be pursuing a PhD Degree (enrolled student).
• Majors in Biological & Computational Sciences.
• Ability to lead and design computational analyses.

Nice To Haves

• Experience with analysis of single cell or spatial transcriptomic data.
• Familiarity with state-of-the-art tools.
• Knowledge and experience with deep generative models.

Responsibilities

• Lead and design computational analyses to address biological questions.
• Develop a deep generative model for cellular deconvolution.
• Assess the accuracy of the method in various tissue samples.

Benefits

• Paid internship for at least the first 12 weeks (40 hours per week).
• Stipend based on location to help alleviate costs.
• Paid holiday time off benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Industry: Professional, Scientific, and Technical Services
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees