The New York Stem Cell Foundation - New York, NY

posted 26 days ago

Full-time - Senior
New York, NY

About the position

The New York Stem Cell Foundation (NYSCF) Research Institute is seeking a Senior Staff/Principal Scientist in AI and Data Science to lead a team focused on developing and deploying machine learning and artificial intelligence pipelines. This role is crucial for extracting disease-relevant insights from large datasets derived from primary and stem cell models. The successful candidate will collaborate with a diverse team of biologists, engineers, and researchers to design multimodal models that integrate various datasets, including genomics and transcriptomics, to advance the understanding of disease progression and therapeutic applications.

Responsibilities

  • Lead and grow a team of data scientists specializing in AI/ML methodologies.
  • Develop and deploy ML tools to unlock phenotypes in in-vitro cell models.
  • Drive projects from inception to results, including designing cohorts to minimize batch effects.
  • Use AI and Computer Vision to identify morphological phenotypic differences between cohorts.
  • Design High Content Imaging (HCI) screens to highlight phenotypic differences between cohorts.
  • Manage image data acquisition, storage, quality analysis, and transfer.
  • Develop quality control and data visualization tools for high-content screens.
  • Communicate technical results and methods clearly, interacting cross-functionally with various teams.
  • Collaborate with computational biologists to integrate complementary datasets, including omics, to produce multimodal models of human disease.
  • Write and procure grants and scientific papers.

Requirements

  • PhD degree in a quantitative discipline (e.g., statistics, computational biology, biomedical engineering, computer science, applied mathematics) or equivalent practical experience.
  • Experience leading a team in the ML space, including interactions with engineers and scientists.
  • 5+ years experience with Python.
  • 5+ years experience with exploratory and statistical data analysis (e.g., linear models, multivariate analysis, predictive modeling, stochastic models).
  • 5+ years experience extracting and cleaning data sets.
  • 5+ years experience in AI and Computer Vision.
  • Familiarity with software engineering practices and experience developing production software and using cloud computing (AWS preferred).
  • Familiarity with microscopes, scientific imaging, and image analysis.
  • Demonstrated willingness to teach others and learn new techniques.
  • Excellent analytical and communication skills.

Nice-to-haves

  • Familiarity with scientific image analysis tools (ImageJ, FIJI).
  • Familiarity with cell biology.

Benefits

  • Comprehensive medical, dental, and vision insurance.
  • 403b retirement plan with 2% employer match (immediate vesting after 90 days).
  • Short and long term disability insurance.
  • Life insurance.
  • Inclusive paid parental leave program.
  • Pretax transit and parking benefits.
  • Legal aid benefits.
  • Wellness benefits.
  • Paid time off including vacation, sick, personal days, flexible holidays, summer flex program, and all company holidays.
  • Visa sponsorship for required work eligibility.
  • Relocation allowance when necessary.
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