Senior Manager, Facilities

Spyglass Pharma•Aliso Viejo, CA

4d•$130,000 - $150,000•Onsite

About The Position

SpyGlass Pharma is a company focused on improving and preserving vision for patients with chronic eye conditions by developing cutting-edge long-term drug delivery products. They have a highly collaborative team with deep expertise in ophthalmology, drug delivery, pharmaceuticals, and medical devices. The company is entering an exciting stage of growth as they advance their lead program through Phase 3 clinical development.

Requirements

Bachelor’s degree in scientific discipline or equivalent experience.
8+ years of progressive facilities management experience in a pharmaceutical, biotech, or life sciences environment, with direct exposure to laboratory and/or GMP manufacturing spaces.
Demonstrated experience building or significantly developing a facilities or EHS function, ideally in a startup or growth-stage company.
Working knowledge of GMP regulations (21 CFR Parts 210/211), laboratory safety standards (OSHA, Cal/OSHA), chemical hygiene requirements, and hazardous waste regulations.
Hands-on, self-directed operator comfortable managing vendors and contractors independently, with strong organizational and communication skills.
Proficiency with equipment tracking systems and standard office productivity tools.

Nice To Haves

Bachelor’s degree in Facilities Management, Engineering, Life Sciences, Environmental Health & Safety, or a related field preferred
professional certification (e.g., CFM, CHMM) a plus.

Responsibilities

Oversee all day-to-day site operations, ensuring spaces are safe, functional, and compliant.
Provide leadership for and continuously improve the company’s Environment, Health & Safety (EHS) program, serving as Safety Officer and ensuring compliance with OSHA, Cal/OSHA, EPA, and all applicable regulations.
Develop and deliver site safety training, maintain chemical hygiene and emergency action plans, and oversee hazardous materials handling and disposal.
Manage a comprehensive preventive maintenance program, including equipment inventory, calibration tracking, and coordination of scheduled service for all lab and manufacturing instrumentation, in accordance with SpyGlass procedures.
Support equipment qualification activities (IQ/OQ/PQ) in collaboration with Quality Assurance.
Identify, onboard, and manage external contractors—including cleaning, HVAC, electrical, plumbing, and specialty lab service vendors—ensuring quality, safety, and compliance on-site.
Negotiate scopes of work and service agreements; oversee contractor performance and approve invoices within delegated authority.
Partner with R&D, Quality, and Regulatory Affairs to maintain facilities documentation and support any inspections and partner audits.
Manage the facilities budget, support capital expenditure planning, and contribute to future site expansion and buildout activities.
Serve as primary liaison with building management and landlord for facility matters and site improvements.