Senior Manager, Downstream Science & Applications

Merck • Bedford, MA

4d • Hybrid

About The Position

The Downstream Science & Applications team within MilliporeSigma's Downstream Applications R&D organization is seeking a Senior Manager to lead a team of senior scientists and engineers focused on advancing applications knowledge for our downstream bioprocessing portfolio. This role sits at the intersection of deep technical expertise, external scientific engagement, and cross-functional collaboration — serving as a critical bridge between our internal R&D capabilities and the broader biopharmaceutical community.

Requirements

• Bachelor's degree in Biochemical Engineering, Chemical Engineering, Biochemistry, Biology, or a related life sciences field with 12-15+ years of relevant experience; or Master's degree with 10-12+ years; or PhD with 8-10+ years
• Demonstrated expertise in downstream bioprocessing, with hands-on experience in chromatography, filtration, or both as an end user or as a downstream applications specialist
• Experience with biopharmaceutical manufacturing processes and familiarity with relevant modalities including monoclonal antibodies, recombinant proteins, or viral vectors
• Proven track record of leading and developing technical teams and delivering high-impact scientific results in an R&D or applications science environment
• Strong scientific communication skills with experience presenting at conferences, authoring technical publications, or contributing to external scientific engagement

Nice To Haves

• Experience serving in a subject matter expert or applications lead capacity on complex, multi-stakeholder R&D projects
• Established network within the downstream bioprocessing community, including relationships with academic institutions, industry consortia, and key opinion leaders

Responsibilities

• Serve as a senior subject matter expert (SME) in downstream bioprocessing, providing technical guidance on the most complex and escalated applications challenges across the filtration and chromatography portfolio
• Lead a team of senior scientists and engineers serving as SMEs and Applications leads on new product development projects to drive early-stage applications development and accelerate commercial readiness and product adoption
• Define and maintain the team's technical priorities, balancing applications support for new products with legacy product needs, and aligning decisions to broader R&D goals and revenue impact
• Partner with customer facing teams to resolve escalated technical questions and provide expert support
• Collaborate with the broader innovation and technology pipeline organization to translate external scientific signals into actionable applications development priorities
• Orchestrate project work across peer R&D teams in the role of Applications Lead, ensuring accountability, quality, and strategic alignment on product development deliverables
• Represent MilliporeSigma at industry conferences, scientific consortia, and academic collaborations, building and maintaining a broad network of downstream bioprocessing contacts to generate insights that inform the team's technical direction and MilliporeSigma's broader downstream portfolio strategy
• Author and contribute to the development of publications, application notes, white papers, and other scientific content that establishes MilliporeSigma's thought leadership in downstream bioprocessing

Benefits

• health insurance
• paid time off (PTO)
• retirement contributions
• other perquisites

What This Job Offers

• Job Type: Full-time
• Career Level: Senior