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Scientist / Senior Scientist, Sequencing Integration
Pacific Biosciences - Menlo Park, CA
posted 3 days ago
About the position
Pacific Biosciences is seeking a Scientist or Senior Scientist to join a dynamic team developing next generation DNA sequencing technology. This position is in a fast-paced environment, interacting with scientists and engineers throughout R&D and from a variety of backgrounds. The selected individual will be working toward the development, integration, and testing of new hardware, chemistry, software, and chips for both the Pacific Biosciences long read (SMRT) and short read (SBB) sequencing systems. This will include working across groups to design, plan and execute experiments.
Responsibilities
- Integration of chemistry with hardware, software, and chips/flowcells
- Development and optimization of workflow scripts for automation systems
- Improvements and optimizations to chemistry reagents and sample preparation
- Data analysis and writing of custom analysis scripts
- Performance testing and troubleshooting on commercial as well as prototype instruments
- Presentation of results at both weekly group and weekly department meetings
- Participation in cross-functional and intragroup experiments and/or projects
Requirements
- PhD in Biophysics, Biochemistry, Molecular Biology, Physics, Chemistry, or related scientific field
- Excellent interpersonal, written, and verbal communication skills
- Experience in analysis of large datasets in R, Python, or a similar analysis package
- Team player: the successful candidate will enjoy working closely with others as a member of an interdisciplinary team
Nice-to-haves
- Experience writing lab automation routines or writing code to control instrument hardware
- Experience with fluidics
- Experience with general laboratory practices (biochemistry/molecular biology)
- Working knowledge of fluorescence and its application
- Practical understanding of the kinetics of enzymatic reactions
- Excellent problem solving/troubleshooting skills
- Attention to detail, careful record-keeping, high level of organization, good verbal and written communication skills
- Able to manage several projects simultaneously
- Self-starter who can operate with minimal supervision
- Experience working with complex, prototype instrumentation is desirable
